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Interview with Jeffrey L. Dangl

机译:Jeffrey L. Dangl的访谈

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Jeff Dangl was born in Grand Rapids, Michigan, USA. His family moved to Redding, in the beautiful north of California, when Jeff was aged 5. He grew up fishing in the lakes and streams of the great North State and hunting ducks and geese on the Pacific Flyway. This introduction to field biology spurred Jeff's interest, and he studied Biological Sciences and English, with a specialization in Modern Literature, at Stanford University as an undergraduate, earning dual Bachelor's degrees in 1981. Jeff had the good fortune to find a summer job in 1978, learning how to run and manage the fluorescence-activated cell sorter (FACS) in the lab of its creator, Prof. Leonard A. Herzenberg, in the Genetics Department at Stanford University School of Medicine. That experience led to an 8 year stint in the Herzenberg lab as an undergraduate, a gap-year research student, and finally as a doctoral student. Jeff created some of the world's first human–mouse chimeric immunoglobulins using the then new recombinant DNA techniques. He switched gears to plant defense responses as an National Science Foundation (NSF) Plant Molecular Biology postdoctoral fellow in Klaus Hahlbrock's department at the Max Planck Institute for Plant Breeding in Cologne, Germany. Jeff lucked into another job, as a Group Leader at the Max Delbrück Laboratory in Cologne, where he was given free rein to apply the emerging model Arabidopsis to problems in plant pathology. Jeff moved to the University of North Carolina (UNC) in 1995 and became a Howard Hughes–Gordon and Betty Moore Plant Science Investigator in 2011. Jeff's research has been recognized by several awards, including elections to the US National Academy of Sciences and the German National Academy (Die Leopoldina). His group's research interests include mechanisms of plant Nod-like receptor (NLR) activation, understanding how pathogen effectors manipulate host cellular machinery, and trying to define rules to assemble synthetic microbial rhizosphere communities that can enhance plant performance. What influenced your path into plant biology?
机译:Jeff Dangl出生于美国密歇根州大急流城。杰夫(Jeff)5岁时,他的家人搬到了加利福尼亚北部美丽的雷丁(Redding)。他在北部大州的湖泊和溪流中钓鱼,并在太平洋飞行道上猎鸭和鹅。现场生物学的介绍激发了Jeff的兴趣,他在斯坦福大学攻读生物文学和英语专业,专门研究现代文学,并于1981年获得双学士学位。Jeff很有幸在1978年找到了一份暑假工作。在斯坦福大学医学院遗传学系的创建者Leonard A. Herzenberg教授的实验室中学习了如何运行和管理荧光激活细胞分选仪(FACS)。这段经历导致他在赫尔森贝格实验室工作了8年,当时是一名本科生,一名差距较大的研究学生,最后是一名博士生。 Jeff使用当时的新重组DNA技术创建了一些世界上第一个人类-小鼠嵌合免疫球蛋白。他在德国科隆的马克斯·普朗克植物育种研究所的克劳斯·哈尔布鲁克的系中担任国家科学基金会(NSF)植物分子生物学博士后研究员,着手研究植物防御反应。 Jeff幸运地担任了另一项工作,在科隆的MaxDelbrück实验室担任组长,在那里他可以自由控制将新兴的拟南芥模型应用于植物病理学问题。杰夫(Jeff)于1995年移居北卡罗来纳大学(UNC),并于2011年成为霍华德·休斯-戈登(Howard Hughes–Gordon)和贝蒂·摩尔(Betty Moore)植物科学研究员。国家科学院(Die Leopoldina)。该小组的研究兴趣包括植物Nod样受体(NLR)活化的机制,了解病原体效应物如何操纵宿主细胞机制,并试图定义规则来组装可增强植物生长性能的合成微生物根际群落。是什么影响了您进入植物生物学的道路?

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