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Nanoparticles for imaging and tumor gene delivery.

机译:用于成像和肿瘤基因传递的纳米粒子。

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摘要

Molecular imaging of receptors expressed on the surface of tumor cells is becoming a major field of investigation in clinical oncology, especially for the detection of cancer at its earliest stages. Nowadays, MRI, microcomputed tomography (microCT), ultrasound, positron emission tomography (PET), optical coherence tomography (OCT), and other major imaging systems are available to scientists and clinicians. Each technique has advantages and limitations, thus making them complementary. We report herein our investigations on the synthesis and use of new probes for small animal imaging as well as on the preparation and use of targeting complexes to deliver specific gene in tumors cells.
机译:在肿瘤细胞表面表达的受体的分子成像正在成为临床肿瘤学的主要研究领域,尤其是对于早期阶段的癌症检测。如今,科学家和临床医生可以使用MRI,微型计算机断层扫描(microCT),超声,正电子发射断层扫描(PET),光学相干断层扫描(OCT)和其他主要成像系统。每种技术都有优点和局限性,因此使它们互补。我们在这里报告我们的调查,有关小动物成像的新探针的合成和使用,以及靶向复合物在肿瘤细胞中传递特定基因的制备和使用。

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