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首页> 外文期刊>Trends in Microbiology >Biofilm formation and dispersal and the transmission of human pathogens
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Biofilm formation and dispersal and the transmission of human pathogens

机译：生物膜的形成和扩散以及人类病原体的传播

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摘要

Several pathogenic bacterial species that are found in the environment can form complex multicellular structures on surfaces known as biofilms. Pseudomonas aeruginosa, Vibrio cholerae and certain species of nontuberculous mycobacteria are examples of human pathogens that form biofilms in natural aquatic environments. We suggest that the dynamics of biofilm formation facilitates the transmission of pathogens by providing a stable protective environment and acting as a nidus for the dissemination of large numbers of microorganisms; both as detached biofilm clumps and by the fluid-driven dispersal of biofilm clusters along surfaces. We also suggest that emerging evidence indicates that biofilm formation conveys a selective advantage to certain pathogens by increasing their ability to persist under diverse environmental conditions.
机译：在环境中发现的几种致病细菌可以在称为生物膜的表面上形成复杂的多细胞结构。铜绿假单胞菌，霍乱弧菌和某些非结核分枝杆菌是在自然水生环境中形成生物膜的人类病原体的例子。我们认为，生物膜形成的动力学通过提供稳定的保护环境和作为传播大量微生物的病菌而促进了病原体的传播。既是分离的生物膜团块，又是流体驱动的生物膜簇沿表面扩散的结果。我们还建议，新出现的证据表明，生物膜的形成通过增加某些病原体在各种环境条件下的持久能力而传达了选择性的优势。

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