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Versatile persistence pathways for pathogens of animals and plants

机译:动植物病原体的多种持久性途径

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The glyoxylate cycle and the glycine cleavage system are part of conserved metabolic pathways involved in the chronic persistence of microorganisms in animal hosts. In the chromosome of the plant pathogen Rhodococcus fascians, the vic locus has been identified as a region containing genes essential for persistence inside induced leafy galls. Sequence analysis showed that this 18-kb locus is syntenic with chromosomal regions of Mycobacterium species that encompass the 'persistence' loci of these mammalian pathogens. Hence, the ability to switch diet inside the host appears to be governed by 'persistence' enzymes that are conserved between pathogens of animals and plants.
机译:乙醛酸循环和甘氨酸裂解系统是保守的代谢途径的一部分,参与了动物宿主中微生物的长期持久存在。在植物病原体法氏红球菌的染色体中,vic基因座已被鉴定为一个区域,该区域包含诱导的多叶胆中持久存在必不可少的基因。序列分析表明,该18kb的基因座与分枝杆菌属物种的染色体区域具有同义性,该区域涵盖了这些哺乳动物病原体的“持久性”基因座。因此,在宿主体内转换饮食的能力似乎受到动植物病原体之间保守的“持久性”酶的控制。

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