• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Trends in Microbiology >Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria
【24h】

Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria

机译：蓝细菌的天然产物生物合成多样性和比较基因组学。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Cyanobacteria are an ancient lineage of slow-growing photosynthetic bacteria and a prolific source of natural products with intricate chemical structures and potent biological activities. The bulk of these natural products are known from just a handful of genera. Recent efforts have elucidated the mechanisms underpinning the biosynthesis of a diverse array of natural products from cyanobacteria. Many of the biosynthetic mechanisms are unique to cyanobacteria or rarely described from other organisms. Advances in genome sequence technology have precipitated a deluge of genome sequences for cyanobacteria. This makes it possible to link known natural products to biosynthetic gene clusters but also accelerates the discovery of new natural products through genome mining. These studies demonstrate that cyanobacteria encode a huge variety of cryptic gene clusters for the production of natural products, and the known chemical diversity is likely to be just a fraction of the true biosynthetic capabilities of this fascinating and ancient group of organisms.
机译：蓝细菌是古老的缓慢生长的光合细菌谱系，是具有复杂化学结构和强大生物活性的天然产物的丰富来源。这些天然产物的大部分仅在少数属中才知道。最近的努力阐明了支撑蓝藻多种天然产物生物合成的机制。许多生物合成机制是蓝细菌所独有的，或者很少被其他生物描述。基因组序列技术的进步催生了蓝藻的大量基因组序列。这使得将已知的天然产物与生物合成基因簇联系起来成为可能，但也通过基因组挖掘加快了对新天然产物的发现。这些研究表明，蓝细菌编码用于生产天然产物的大量隐蔽基因簇，已知的化学多样性可能只是这一迷人而古老的生物体的真实生物合成能力的一小部分。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号