Type III machines of Gram-negative bacteria: delivering the goods

Luisa W. Cheng; Olaf Schneewind

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Type III machines of Gram-negative bacteria: delivering the goods

机译：革兰氏阴性细菌的III型机器：运送货物

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Many Gram-negative pathogens use a type III secretion machine to translocate protein toxins across the bacterial cell envelope. Pathogenic Yersinia spp. export at least 14 Yop proteins via a type III machine, which recognizes secretion substrates by signals encoded in yop mRNA or chaperones bound to unfolded Yop proteins. During infection, substrate recognition appears to be regulated in a manner that allows the Yersinia type III pathway to direct Yops to the bacterial envelope, the extracellular medium or into the cytosol of host cells.

机译：许多革兰氏阴性病原体使用III型分泌机在整个细菌细胞膜中转运蛋白毒素。致病性耶尔森氏菌通过III型机器输出至少14种Yop蛋白，该机器通过yop mRNA或与未折叠的Yop蛋白结合的分子伴侣编码的信号识别分泌底物。在感染期间，底物识别似乎以允许耶尔森氏菌III型途径将Yops引导至细菌包膜，细胞外培养基或宿主细胞胞质溶胶的方式进行调节。

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《Trends in Microbiology》 |2000年第5期|共7页
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Luisa W. Cheng; Olaf Schneewind;
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1. Type III machines of Gram-negative bacteria: delivering the goods [J] . Luisa W. Cheng, Olaf Schneewind Trends in Microbiology . 2000,第5期

机译：革兰氏阴性细菌的III型机器：运送货物
2. The Role of the Type-III Secretion System of Gram-Negative Bacteria in the Regulation of Chronic Infections [J] . N. A. Zigangirova, L. N. Nesterenko, I. L. Tiganova, Molecular Genetics , Microbiology and Virology: Molekulyarnaya Genetika , Mikrobiologiya i Virusologiya . 2012,第3期

机译：革兰氏阴性细菌的III型分泌系统在慢性感染调节中的作用
3. The Bactericidal Activity of the C-type Lectin RegIIIβ against Gram-negative Bacteria involves Binding to Lipid A [J] . Tsuyoshi Miki, Otto Holst, Wolf-Dietrich Hardt The Journal of biological chemistry . 2012,第41期

机译：C型凝集素Regiiiβ对革兰阴性细菌的杀菌活性涉及与脂A的结合
4. Predicting Protein Subcellular Localizations for Gram-Negative Bacteria Using DP-PSSM and Support Vector Machines [C] . Juan E.Y.T., Li W.J., Jhang J.H., Complex, Intelligent and Software Intensive Systems, 2009. CISIS '09 . 2009

机译：使用DP-PSSM和支持向量机预测革兰氏阴性细菌的蛋白质亚细胞定位
5. Identification and characterization of Type III secretion effector proteins in Gram-negative bacteria. [D] . Panina, Ekaterina Mikhailovna. 2008

机译：革兰氏阴性细菌中III型分泌效应蛋白的鉴定和表征。
6. Antibodies Inhibiting the Type III Secretion System of Gram-Negative Pathogenic Bacteria [O] . Julia A. Hotinger, Aaron E. May 2020

机译：抑制革兰氏阴性致病菌III型分泌系统的抗体
7. Epigallocatechin gallate inhibits the type III secretion system of Gram-negative enteropathogenic bacteria under model conditions [O] . Noboru Nakasone, Naomi Higa, Claudia Toma, 2017

机译：EpigallocateChin Gallate在模型条件下抑制革兰氏阴性肠球菌细菌III型分泌系统
8. Heterogeneity of Lipid A: Comparison of Lipid A Types from Different Gram-Negative Bacteria [R] . Mattsby-Baltzer, I., Gemski, P., Alving, C. R. 1984

机译：脂质a的异质性：来自不同革兰氏阴性细菌的脂质a类型的比较

Type III machines of Gram-negative bacteria: delivering the goods

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