Lipid chemotaxis and signal transduction in Myxococcus xanthus

Daniel B. Kearns; Lawrence J. Shimkets

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Lipid chemotaxis and signal transduction in Myxococcus xanthus

机译：黄黏球菌的脂质趋化性和信号转导

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The lipid phosphatidylethanolamine (PE) is the first chemoattractant to be described for a surface-motile bacterium. In Myxococcus xanthus, the specific activity of PE is determined by its fatty acid components. Two active species have been identified: dilauroyl PE and dioleoyl PE. Excitation to dilauroyl PE requires fibril appendages and the presence of two cytoplasmic chemotaxis systems, of which one (Dif) appears to mediate excitation and the other (Frz) appears to mediate adaptation. A possible mechanism for fibril-mediated signal transduction is discussed, along with the potential roles for PE chemotaxis in the context of the M. xanthus life cycle.

机译：脂质磷脂酰乙醇胺（PE）是表面运动细菌中第一个描述的化学吸引剂。在黄色葡萄球菌中，PE的比活性由其脂肪酸成分决定。已经鉴定出两种活性物质：二月桂酰PE和二油酰PE。对二月桂酰PE的激发需要原纤维附件，并且存在两个胞质趋化性系统，其中一个（Dif）似乎介导兴奋，而另一个（Frz）似乎介导适应。讨论了原纤维介导的信号转导的可能机制，以及在黄花木兰生命周期中PE趋化性的潜在作用。

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《Trends in Microbiology》 |2001年第3期|共4页
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Daniel B. Kearns; Lawrence J. Shimkets;
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1. Lipid chemotaxis and signal transduction in Myxococcus xanthus [J] . Daniel B. Kearns, Lawrence J. Shimkets Trends in Microbiology . 2001,第3期

机译：黄黏球菌的脂质趋化性和信号转导
2. Analysis of the Frz signal transduction system of Myxococcus xanthus shows the importance of the conserved C-terminal region of the cytoplasmic chemoreceptor FrzCD in sensing signals [J] . Bustamante VH, Martinez-Flores I, Vlamakis HC, Molecular Microbiology . 2004,第5期

机译：对黄色葡萄球菌的Frz信号转导系统的分析表明，胞质化学感受器FrzCD的保守C端区域在感应信号中的重要性
3. The FruA signal transduction protein provides a checkpoint for the temporal co-ordination of intercellular signals in Myxococcus xanthus development. [J] . Ellehauge E, Norregaard-Madsen M, Sogaard-Andersen L Molecular Microbiology . 1998,第4期

机译：FruA信号转导蛋白为黄色粘球菌发展过程中细胞间信号的时间协调提供了一个检查点。
4. Examination of the Role of Lipid Rafts in GPCR Signal Transduction Using Plasmon Waveguide Resonance (PWR) Spectroscopy [C] . Victor J. Hruby, Isabel D. Alves, Savitha Devanathan American Peptide Symposium . 2006

机译：检查脂肪筏在使用等离子体波导共振（PWR）光谱法中的GPCR信号转导中的作用
5. Novel regulatory mechanisms of a chemotaxis pathway in the gliding bacterium Myxococcus xanthus. [D] . Astling, David Paul. 2003

机译：滑移细菌黄曲霉中趋化性途径的新型调控机制。
6. C factor a cell-surface-associated intercellular signaling protein stimulates the cytoplasmic Frz signal transduction system in Myxococcus xanthus. [O] . L Søgaard-Andersen, D Kaiser 1996

机译：C因子是一种与细胞表面相关的细胞间信号转导蛋白可刺激粘液黄单胞菌的胞质Frz信号转导系统。
7. C factor, a cell-surface-associated intercellular signaling protein, stimulates the cytoplasmic Frz signal transduction system in Myxococcus xanthus. [O] . Søgaard-Andersen, L, Kaiser, D 1996

机译：C因子是一种与细胞表面相关的细胞间信号转导蛋白，可刺激粘液黄单胞菌的胞质Frz信号转导系统。
8. Characterization of asgC, a Gene Required for Cell-Cell Signaling in Myxococcus xanthus [R] . Plamann, L. S. 2000

机译：asgC的表征，这是一种在myxococcus xanthus中细胞 - 细胞信号传导所需的基因

Lipid chemotaxis and signal transduction in Myxococcus xanthus

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