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Nationwide integrated mapping of three neglected tropical diseases in Togo: Countrywide implementation of a novel approach

机译:在多哥对三种被忽视的热带病进行全国综合制图:在全国范围内实施新方法

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Objective To conduct a nationwide integrated neglected tropical disease (NTD) prevalence survey to define the need for public health interventions using an innovative mapping protocol. Methods Two villages were selected in every peripheral health unit in endemic districts: 29 districts for schistosomiasis and STH, 15 of them for trachoma. In each village, 15 children aged 6-9years at a randomly selected school were tested. An additional convenience sample of 35 children aged 1-5years underwent an eye examination for trachoma. This integrated mapping was followed by a 20-cluster trachoma survey in each district that surpassed the WHO-defined threshold of 10% prevalence of trachomatous inflammation-follicular (TF). Results A total of 1096 villages were surveyed in <6weeks. The district prevalence of schistosomiasis ranged from 2 to 49% and of STH from 5 to 70%, with prevalence at the village level ranging from 0 to 100% for both diseases. Two districts passed the threshold of 10% for active trachoma, but the cluster survey indicated this was because of misclassification bias and that the real prevalence was <1%. Conclusion Results of this mapping were used by the MoH and partners to plan integrated mass drug administration (MDA). Mass drug administration for trachoma was not implemented as no district passed the threshold requiring public health intervention.
机译:目的开展一项全国性的综合性被忽视热带病(NTD)患病率调查,以使用创新的测绘方案确定对公共卫生干预措施的需求。方法在地方病流行区的每个外围卫生单位中选出两个村庄:血吸虫病和STH区29个,沙眼区15个。在每个村庄中,对一所随机选择的学校中的15名6-9岁的儿童进行了测试。另对35名1-5岁儿童进行了便利检查,以进行眼沙眼检查。进行此综合绘图后,在每个地区进行了20个集群的沙眼调查,调查结果超过了WHO定义的10%的气管炎性炎症滤泡(TF)患病率阈值。结果<6周内对1096个村庄进行了调查。血吸虫病的地区患病率在2%至49%之间,STH的患病率在5%至70%之间,两种疾病在村级患病率在0%至100%之间。两个地区的活动性沙眼通过了10%的阈值,但整群调查表明,这是由于分类错误造成的,实际患病率小于1%。结论卫生部及其合作伙伴使用了该图谱的结果,以计划进行大规模药物综合管理(MDA)。由于没有地区超过要求公共卫生干预的门槛,因此未实施针对沙眼的大规模药物管理。

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