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A retrospective study on the epidemiology of foot-and-mouth disease in Bhutan

机译:不丹口蹄疫流行病学回顾性研究

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A retrospective study on the outbreaks of foot-and-mouth disease (FMD) in Bhutan, between the years 1996 and 2008, based on the data collected through passive surveillance, was undertaken. A total of 230 outbreaks of FMD at sub-district level were recorded in 299 villages located in 19 out of the 20 districts in the country. There were no significant differences between the years (P=0.998) or months (P=0.989) on the incidence of FMD. The sub-districts in the north (altitude >1,000m above mean sea level) had significantly (P=0.008) higher incidences of outbreaks in winter than in summer. The sub-districts that shared border with India had significantly more outbreaks than those that didn't (P=0.001). Cattle were the most predominant species affected being involved in all of the outbreaks reported. Serotype O, which constituted 70.6% of the outbreaks typed was the most predominant serotype prevalent in Bhutan followed by A (16.7%), Asia 1 (8.8%), and C (3.9%). Cattle density was significantly positively correlated (P=0.023) with the incidence of disease. Three waves of outbreaks of epidemic proportions were reported in 1997/1998, 2002/2003, and 2007/2008 due to the PanAsia strain of the O serotype. The study highlights the incursion of the PanAsia strain of the O serotype into the country, possibly, through the transboundary movement of animals and the need for active surveillance of FMD, especially at the border areas. The study also highlights the significance of the O serotype and cattle as the main indicator species in the epidemiology of FMD in Bhutan. The findings from this study can be used as baseline epidemiological data for further research to understand the epidemiology of FMD in Bhutan.
机译:根据通过被动监测收集的数据,对1996年至2008年间不丹的口蹄疫暴发进行了回顾性研究。在该国20个地区中有19个地区的299个村庄中,共记录了230例次地区口蹄疫暴发。在FMD的发生年份(P = 0.998)或月份(P = 0.989)之间没有显着差异。北部的分区(海拔高于平均海平面> 1,000m)冬季的暴发率明显高于夏季(P = 0.008)。与印度共有边界的街道爆发病的数量明显多于未与印度毗邻的街道(P = 0.001)。牛是受影响最大的物种,涉及所有已报告的疫情。在不丹流行的最主要的血清型中,O型血清型占疫情的70.6%,其次是A(16.7%),Asia 1(8.8%)和C(3.9%)。牛密度与疾病的发病率显着正相关(P = 0.023)。据报道,由于泛亚型O型血清型,1997 / 1998、2002 / 2003和2007/2008年爆发了三波流行病。这项研究强调了可能是由于动物的越境转移以及对口蹄疫的积极监测的需要,特别是在边境地区,泛亚型O血清型的泛亚株进入该国。该研究还强调了O血清型和牛作为不丹FMD流行病学主要指标物种的重要性。这项研究的结果可以用作基础流行病学数据,以供进一步研究以了解不丹口蹄疫的流行病学。

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