• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Tropical Animal Health and Production >Evaluation of mammary gland immunity and therapeutic potential of Tinospora cordifolia against bovine subclinical mastitis
【24h】

Evaluation of mammary gland immunity and therapeutic potential of Tinospora cordifolia against bovine subclinical mastitis

机译：廷氏孢子虫对牛亚临床乳腺炎的乳腺免疫力和治疗潜力的评估

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Enhancement of the diseased mammary gland immunity and therapeutic potential of hydro-methanolic extract of Tinospora cordifolia (T. cordifolia; stem) in bovine subclinical mastitis was investigated. Somatic cell count (SCC), total bacterial count (TBC), phagocytic activity, and leukocyte lysosomal enzymes like myeloperoxidase and acid phosphatase activity and Interleukin-8 (IL-8) level were evaluated after intramammary infusion of hydro-methanolic extract (stem) of T.cordifolia in diseased cows. The qualitative analysis of the extract revealed the presence of polysaccharide, phenol, alkaloid, and protein. Intramammary infusion of hydro-methanolic extract of T. cordifolia treatment initially enhanced the SCC; thereafter, significant reduction in cell count (P<0.05) was observed on day 15 of the treatment period, however, reduction in TBC was observed from day 3 onwards. The phagocytic activity of milk polymorphonuclear cells enhanced in the diseased cows treated with the T. cordifolia extract. Similarly, the lysosomal enzyme content of the milk polymorphonuclear cells enhanced significantly (P<0.05) in diseased cows treated with T. cordifolia. The IL-8 level in milk serum also increased significantly (P<0.05) in diseased cows treated with the herb extract. The results suggest that the hydro-methanolic extract of T.cordifolia (stem) possesses antibacterial and immunomodulatory properties. In the present study, the biological activity of the Tinospora cordifolia extract at standardized dose against bovine subclinical mastitis is reported for the first time. Development of alternative therapy with medicinal plants is an option for livestock farmers who are not allowed to use the conventional allopathic drugs under certain farming system or cannot afford to use allopathic drugs.
机译：研究了患病的乳腺免疫力的增强和在牛亚临床性乳腺炎中的心叶忍冬（T. cordifolia; stem）的乙醇甲醇提取物的治疗潜力。在乳房内输注水-甲醇提取物（干）后，评估了体细胞计数（SCC），总细菌计数（TBC），吞噬活性和白细胞溶酶体酶，例如髓过氧化物酶和酸性磷酸酶活性以及白细胞介素8（IL-8）的水平。病牛的T.cordifolia提取物的定性分析表明存在多糖，苯酚，生物碱和蛋白质。乳房内滴入棉铃虫的水-甲醇提取物最初会增强SCC。此后，在治疗期的第15天观察到细胞计数显着减少（P <0.05），但是从第3天开始观察到TBC减少。在用T. cordifolia提取物治疗的患病母牛中，牛奶多形核细胞的吞噬活性增强。同样，在用T. cordifolia处理的患病母牛中，牛奶多形核细胞的溶酶体酶含量显着增加（P <0.05）。用草药提取物治疗的患病奶牛，乳清中的IL-8水平也显着增加（P <0.05）。结果表明，T.cordifolia（茎）的水-甲醇提取物具有抗菌和免疫调节特性。在本研究中，首次报道了标准剂量的紫草提取物对牛亚临床乳腺炎的生物学活性。对于不允许在某些耕作制度下使用常规同种疗法药物或无力使用同种疗法药物的牲畜养殖者而言，开发药用植物替代疗法是一种选择。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号