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Liver metabolic and histopathological profile in finishing lambs fed licuri (Syagrus coronata(Mart.)Becc.) cake

机译:饲喂甘草(Syagrus coronata(Mart。)Becc。)蛋糕的羔羊的肝脏代谢和组织病理学特征

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The objective of this study was to determine the impact of including licuri cake in the diet of Santa Ins crossbred finishing lambs by examining their liver metabolic and histopathological profile. Forty-four uncastrated lambs with an average age of 6 months and an average weight of 21.2 kg +/- 2.7 kg. The animals were fed diets with 40 % Tifton 85 hay and 60 % of a mixture consisting of corn and soybean meal, 1 % urea, a mineral-vitamin premix, and an inclusion of licuri cake at a level of 0, 8, 16, and 24 % of the dietary dry matter (DM), which composed the treatments. The experimental design was completely randomized, and the data were analyzed by variance and regression analyses. The animals were confined in individual stalls for 70 days. Blood was collected on the last day of the experimental period, and metabolite, protein, energy, and enzyme profiles of the liver were determined for these samples. Histopathological evaluations of the liver parenchyma were also undertaken. The increase in the level of the licuri cake in the diet caused a linear increase (P 0.05) in the serum urea content. The protein metabolism was not affected by the licuri cake inclusion levels in the diet. Regarding energy metabolism, a linear increase (P 0.01) was observed in the serum triglyceride concentrations, but there were no effects on serum cholesterol levels. Regarding the functioning of the liver and muscle, the inclusion of the licuri cake had no effect on the enzymatic activities, except on gamma-glutamyltransferase, which decreased linearly (P 0.05). The values found for the evaluated parameters varied within a range considered normal for this species. In the postmortem examination at slaughter, no macroscopic alterations in the liver were observed. Histopathological analysis revealed the presence of discrete and nonspecific alterations common to all treatments, suggesting no effect of the level of inclusion of the licuri cake. The use of the licuri cake in composing up to 24 % of the diet did not cause metabolic or liver disorders in the lambs.
机译:这项研究的目的是通过检查它们的肝脏代谢和组织病理学特征来确定在圣印斯杂交杂种羔羊的饮食中加入甘露酸蛋糕的影响。四十四只未cast割的羔羊,平均年龄为6个月,平均体重为21.2公斤+/- 2.7公斤。用40%Tifton 85干草和60%的玉米和大豆粉混合物,1%的尿素,矿物质维生素预混料以及含有licuri饼的混合物(0、8、16,构成治疗的膳食干物质(DM)占24%。实验设计完全随机化,并通过方差和回归分析对数据进行分析。将动物限制在单独的摊位中70天。在实验期的最后一天收集血液,并确定这些样品的肝脏代谢物,蛋白质,能量和酶谱。还进行了肝实质的组织病理学评估。日粮中甘草饼含量的增加导致血清尿素含量线性增加(P <0.05)。蛋白质的代谢不受饮食中甘草饼中夹杂物含量的影响。关于能量代谢,血清甘油三酸酯浓度呈线性增加(P <0.01),但对血清胆固醇水平没有影响。关于肝脏和肌肉的功能,除了甘草-谷氨酰转移酶呈线性下降(P <0.05)外,加入甘草酸对酶活性没有影响。发现的评估参数值在该物种正常范围内变化。在宰杀后的尸检中,未观察到肝脏的宏观变化。组织病理学分析显示存在所有治疗共有的离散的和非特异性的改变,表明对licuri蛋糕的包合水平没有影响。在最多占饮食的24%中使用licuri蛋糕不会在羔羊中引起新陈代谢或肝脏疾病。

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