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首页> 外文期刊>Trends in Neurosciences >Interneuron Diversity series: Interneuronal neuropeptides--endogenous regulators of neuronal excitability.
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Interneuron Diversity series: Interneuronal neuropeptides--endogenous regulators of neuronal excitability.

机译：神经元间多样性系列：神经元间神经肽-神经元兴奋性的内源性调节剂。

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Interneurons are often classified according to neuropeptide content. However, it is becoming increasingly clear that neuropeptides are more than convenient neurochemical markers and can act as important modulators of neuronal activity. Recent advances in understanding neuropeptide release and physiological actions suggest that the interneuronal system of neuropeptides is crucial for maintaining appropriate brain function under normal and pathophysiological conditions. In particular, interneuronal neuropeptides appear to play roles in cognition and as endogenous anti-epileptic agents. This article describes current understanding of the conditions under which neuropeptides are released from interneurons, their specific effects on neuronal excitability and synaptic transmission, and the consequences of their loss of function.
机译：中间神经元通常根据神经肽含量分类。然而，越来越清楚的是，神经肽不仅仅是方便的神经化学标记，而且可以充当神经元活性的重要调节剂。在了解神经肽释放和生理作用方面的最新进展表明，神经肽的神经内系统对于在正常和病理生理条件下维持适当的脑功能至关重要。特别地，神经元间神经肽似乎在认知中起作用并且作为内源性抗癫痫药。本文介绍当前对神经元从神经元中释放的条件的理解，它们对神经元兴奋性和突触传递的特定作用，以及其功能丧失的后果。

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