Linking DNA damage and neurodegeneration.

Rolig RL; McKinnon PJ

首页> 外文期刊>Trends in Neurosciences >Linking DNA damage and neurodegeneration.

【24h】

Linking DNA damage and neurodegeneration.

机译：将DNA损伤与神经变性联系起来。

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Many human pathological conditions with genetic defects in DNA damage responses are also characterized by neurological deficits. These neurological deficits can manifest themselves during many stages of development, suggesting an important role for DNA repair or processing during the development and maintenance of the nervous system. Although the molecular neuropathology associated with such deficits is largely unknown, many of the responsible gene defects have been identified. The current rapid progress in elucidation of molecular details following gene identification should provide further insight into the importance of DNA processing in nervous system function.

机译：DNA损伤反应中具有遗传缺陷的许多人类病理状况也以神经功能缺损为特征。这些神经系统缺陷可在发育的许多阶段表现出来，表明在神经系统发育和维持过程中DNA修复或加工的重要作用。尽管与这种缺陷相关的分子神经病理学基本上是未知的，但是已经鉴定出许多负责的基因缺陷。在鉴定基因之后，目前在阐明分子细节方面的迅速进展应提供对DNA加工在神经系统功能中的重要性的进一步认识。

著录项

来源
《Trends in Neurosciences》 |2000年第9期|共8页
作者
Rolig RL; McKinnon PJ;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
DNA Damage; Nerve Degeneration; Neurodegenerative Diseases; DNA损伤; 神经变性; 神经变性疾病;

机译：DNA Damage;Nerve Degeneration;Neurodegenerative Diseases;DNA损伤;神经变性;神经变性疾病;

相似文献

外文文献
中文文献
专利

1. Linking DNA damage and neurodegeneration. [J] . Rolig RL, McKinnon PJ Trends in Neurosciences . 2000,第9期

机译：将DNA损伤与神经变性联系起来。
2. SUMO Modification of the Base Excision Repair Protein, Ntg1, Links DNA Damage and DNA Damage Response. [J] . McPherson A. J., Swartzlander D. B., Limpose K. L., Environmental and molecular mutagenesis. . 2016,第Suppla1期

机译：基本切除修复蛋白Ntg1的SUMO修饰将DNA损伤和DNA损伤反应联系起来。
3. SUMO Modification of the Base Excision Repair Protein, Ntg1, Links DNA Damage and DNA Damage Response [J] . McPherson A. J., Swartzlander D. B., Bauer N. C., Environmental and molecular mutagenesis. . 2015,第Suppla1期

机译：碱基切除修复蛋白Ntg1的SUMO修饰将DNA损伤和DNA损伤反应联系起来
4. satDNA Analyzer 1.2 as a Valuable Computing Tool for Evolutionary Analysis of Satellite-DNA Families: Revisiting Y-Linked Satellite-DNA Sequences of Rumex (Polygonaceae) [C] . Rafael Navajas-Perez, Manuel Ruiz Rejon, Manuel Garrido-Ramos, Bioinformatics Research and Development; Lecture Notes in Bioinformatics; 4414 . 2007

机译：satDNA分析仪1.2作为对卫星DNA家族进行进化分析的重要计算工具：重新审视Rumex（ly科）的Y连锁卫星DNA序列。
5. Generation of site-specific DNA-polypeptide cross-links mediated by Schiff base chemistry: A novel strategy to investigate the cellular pathways that repair DNA-protein cross-link damage. [D] . Kurtz, Andrew James. 2003

机译：由席夫碱化学介导的位点特异性DNA多肽交联的生成：研究修复DNA蛋白质交联损伤的细胞途径的新策略。
6. UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation [O] . Marjorie Brand, Jonathan G. Moggs, Mustapha Oulad-Abdelghani, 2001

机译：TFTC复合物中的紫外线破坏的DNA结合蛋白将DNA损伤识别与核小体乙酰化联系起来
7. Linking DNA Damage and Age-Related Promoter DNA Hyper-Methylation in the Intestine [O] . Torsten Thalheim, Maria Herberg, Joerg Galle 2018

机译：将DNA损伤与年龄相关的启动子DNA超甲基化联系在肠中

Linking DNA damage and neurodegeneration.

摘要

著录项

相似文献

相关主题

期刊订阅