Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase

Seung-Heon Yoon; John F.Robyt

首页> 外文期刊>Carbohydrate research >Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase

【24h】

Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase

机译：通过阿卡波糖与环麦芽六糖和环麦芽糊精葡糖基转移酶的反应，将麦芽糖糊精添加到阿卡波糖的非还原端

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

New kinds of acarbose analogues were synthesized by the reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase (CGTase). Three major CGTase coupling products were separated and purified by Bio-Gel P2 gel-permeation chromatogarphy. Digestion of the three products by beta-amylase and glucoamylase showed that they were composed of maltohexaose (G6), maltododecaose (G12), and maltooctadecaose (G18), respectively, attached to the nonreducing-end of acarbose. ~(13)C NMR of the glucoamylase product (D-glucopyranosyl-acarbose) showed that the D-glucose moiety was attached #alpha#-to the C-4-OH group of the nonreducing-end cyclohexene ring of acarbose, indicating that the maltodextrins were attached #alpha#-(1->4) to the nonreducing-end cyclohexene of acarbose.

机译：通过阿卡波糖与环麦芽六糖和环麦芽糊精葡糖基转移酶（CGTase）的反应合成了新型的阿卡波糖类似物。通过Bio-Gel P2凝胶渗透色谱法分离和纯化了三种主要的CGTase偶联产物。 β-淀粉酶和葡糖淀粉酶对这三种产物的消化表明，它们分别由麦芽六糖（G6），麦芽十二烷基蔗糖（G12）和麦芽十八烷基蔗糖（G18）组成，分别附着于阿卡波糖的非还原末端。葡糖淀粉酶产物（D-吡喃葡萄糖基-阿卡波糖）的〜（13）C NMR表明，D-葡萄糖部分与α-糖的非还原端环己烯环的C-4-OH基团＃alpha＃-连接，表明将麦芽糊精#alpha＃-（1-> 4）连接至阿卡波糖的非还原端环己烯。

著录项

来源
《Carbohydrate research》 |2002年第6期|共8页
作者
Seung-Heon Yoon; John F.Robyt;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类糖（醣）;有机化学;
关键词
acarbose analogues; cyclomaltohexaose; cyclomaltodextrin glucanyltransferase; transglycosylation reactions; maltohexaose; maltododecaose; maltooctadecaose; ~(13)C NMR spectroscopy;

机译：阿卡波糖类似物;环麦芽六糖;环麦芽糊精葡聚糖基转移酶;转糖基化反应;麦芽六糖;麦芽十二烷基;麦芽十八烷基;〜（13）C NMR光谱;

相似文献

外文文献
中文文献
专利

1. Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase [J] . Seung-Heon Yoon, John F.Robyt Carbohydrate research . 2002,第6期

机译：通过阿卡波糖与环麦芽六糖和环麦芽糊精葡糖基转移酶的反应，将麦芽糖糊精添加到阿卡波糖的非还原端
2. Synthesis of dopamine and L-DOPA-alpha-glycosides by reaction with cyclomaltohexaose catalyzed by cyclomaltodextrin glucanyltransferase [J] . Yoon SH, Fulton DB, Robyt JF Carbohydrate research . 2009,第17期

机译：环麦芽糊精葡聚糖基转移酶与环麦芽六糖反应合成多巴胺和L-DOPA-α-糖苷
3. Optimized synthesis of specific sizes of maltodextrin glycosides by the coupling reactions of Bacillus macerans cyclomaltodextrin glucanyltransferase [J] . Seung-Heon Yoon, John F.Robyt Carbohydrate research . 2006,第2期

机译：通过Macerans芽孢杆菌环麦芽糖糊精葡聚糖转移酶的偶联反应优化麦芽糖糊精糖苷特定大小的合成
4. In-Vitro and In-Vivo Evaluation of Novel Controlled Release Polysaccharidic Matrix of Acarbose [C] . R.V. Kumar, V.R. Sinha Annual meeting exposition of the Controlled Release Society . 2010

机译：新型阿卡波糖控释多糖基质的体外和体内评价
5. Extraction of Raw and Cooked Pinto Beans Using Response Surface Methodology to Recover Total Flavonoids and Condensed Tannins to Inhibit Alpha Amylase and Alpha Glucosidase Alone or Combined with Acarbose [D] . Aldawsari, Mohammed Saeed. 2018

机译：利用响应表面方法提取原料和煮熟的泛胶豆，以恢复总黄酮和浓缩的单宁，以抑制α淀粉酶和α葡糖苷酶单独或与氨基糖组合
6. Acarbose a Pseudooligosaccharide Is Transported but Not Metabolized by the Maltose-Maltodextrin System of Escherichia coli [O] . Claudia Brunkhorst, Christian Andersen, Erwin Schneider 1999

机译：阿卡波糖一种伪低聚糖被大肠杆菌的麦芽糖-麦芽糖糊精系统转运但未被代谢
7. Acarbose, a Pseudooligosaccharide, Is Transported but Not Metabolized by the Maltose-Maltodextrin System of Escherichia coli [O] . Claudia Brunkhorst, Christian Andersen, Erwin Schneider 1999

机译：氨基糖，假脱核苷酸，由大肠杆菌的麦芽糖 - 麦芽糖糊精系统运输但未代谢
8. Reactions of Metal-Metal Triple Bonds. 7. Addition of the Halogens (Cl2, Br2 and I2) and Diisopropylperoxide to Hexaisopropoxydimolybdenum (M-M). Dinuclear Oxidative-Addition Reactions Accompanied by Metal-Metal Bond Order Changes [R] . Chisholm, M. H., Kirkpatrick, C. C., Huffman, J. C. 1980

机译：金属 - 金属三键的反应。 7.将卤素（Cl2，Br2和I2）和二异丙基过氧化物加入到六异丙氧基二钼（m-m）中。伴随金属 - 金属键序改变的双核氧化 - 加成反应

Addition of maltodextrins to the nonreducing-end of acarbose by reaction of acarbose with cyclomaltohexaose and cyclomaltodextrin glucanyltransferase

摘要

著录项

相似文献

相关主题

期刊订阅