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How to evaluate the effectiveness of catheter-directed thrombolytic therapy in pulmonary embolism

机译:如何评估导管溶栓治疗肺栓塞的有效性

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摘要

We congratulate the authors on their successful study. Although a relatively new method, the catheter-directed ultrasound-accelerated thrombolysis (USAT) was reported in various studies to yield satisfactory results in the treatment of acute pulmonary embolism. As in the present study,1 the effectiveness of the treatment has been evaluated on the basis of the degree of thrombolysis confirmed by computed tomography (CT) in the clot impacted in the pulmonary artery following the therapy. However, Engelhardt et al assessed the right-left ventricular (RV/LV) diameter ratios on CT, detecting a decrease in the former ratio depending on the right ventricular shrinkage due to regression of the right ventricular failure following USAT therapy. Of the patients in whom we performed USAT in our clinic, we noted a dramatic improvement in the symptoms and a decrease in the RV/LV ratio following the procedure in one, although a noncomplete lysis was confirmed on postoperative CT in the pulmonary arterial clot.
机译:我们祝贺作者的成功研究。尽管是一种相对较新的方法,但在各种研究中均报道了导管引导的超声加速溶栓术(USAT)在治疗急性肺栓塞方面取得了令人满意的结果。如本研究一样,1治疗的有效性已根据通过计算机断层扫描(CT)确认的治疗后受累于肺动脉的血凝块的溶栓程度进行了评估。但是,Engelhardt等人评估了CT上的右心室(RV / LV)直径比,并根据USAT治疗后右心衰竭的消退,根据右心室收缩情况检测前者的比率降低。在我们的诊所中进行USAT的患者中,尽管在术后CT证实肺动脉血栓中证实存在不完全溶解,但我们注意到在该手术后,症状显着改善,RV / LV比降低。

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