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首页> 外文期刊>Veterinary Dermatology >A case-control study of the risk factors for canine juvenile-onset generalized demodicosis in the USA.
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A case-control study of the risk factors for canine juvenile-onset generalized demodicosis in the USA.

机译：在美国进行的犬幼年性全身性蠕虫病危险因素的病例对照研究。

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摘要

Canine juvenile-onset generalized demodicosis (JOGD) is a common skin disorder suspected to be associated with multiple risk factors, including breed predispositions. These risk factors have not been well documented in a large population. A retrospective case-control study was conducted by searching the electronic medical records of 1189906 dogs examined at 600 hospitals during 2006 in order to assess the risk factors associated with JOGD in the USA. Multivariate analyses were conducted using logistic regression to estimate the relative risk with the odds ratio for variables hypothesized to influence the risk for canine demodicosis. Breeds (odds ratio) found to have the greatest association with a diagnosis of JOGD were American Staffordshire terrier (35.6), Staffordshire bull terrier (17.1) and Chinese shar-pei (7.2). Nonbreed risk factors (odds ratio) significantly associated with a diagnosis of JOGD were the diagnosis of pyoderma (5.5), coccidiosis (2.7) or hookworms (1.5), short coat (1.9) and nonenrolment in a preventative care wellness plan (1.5). Documenting these risk factors may help veterinarians to prioritize differential diagnoses and will aid in the design of prospective studies to elucidate the pathogenesis of demodicosis in dogs.Digital Object Identifier http://dx.doi.org/10.1111/j.1365-3164.2010.00922.x
机译：犬幼年性全身蠕虫病（JOGD）是一种常见的皮肤病，被怀疑与多种危险因素有关，包括品种易感性。这些风险因素尚未在大量人群中得到充分记录。回顾性病例对照研究是通过搜索2006年在600家医院检查的1189906条狗的电子病历进行的，目的是评估与美国JOGD相关的危险因素。使用logistic回归进行多变量分析，以假设风险影响犬瘟疫风险的变量的比值比评估相对风险。被发现与JOGD诊断最大相关的品种（比率）是美国斯塔福德郡梗（35.6），斯塔福德郡斗牛梗（17.1）和中国沙皮犬（7.2）。与JOGD的诊断显着相关的非繁殖危险因素（几率）是脓皮病（5.5），球虫病（2.7）或钩虫（1.5），短大衣（1.9）以及未加入预防保健计划（1.5）。记录这些危险因素可能有助于兽医优先区分诊断，并有助于设计前瞻性研究以阐明狗的蠕虫病发病机理。Digital Object Identifier http://dx.doi.org/10.1111/j.1365-3164.2010。 00922.x

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