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首页> 外文期刊>Veterinary Microbiology >Two fiber genes of nearly equal lengths are a common and distinctive feature of Fowl adenovirus C members
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Two fiber genes of nearly equal lengths are a common and distinctive feature of Fowl adenovirus C members

机译：两种长度几乎相等的纤维基因是家禽腺病毒C成员的共同特征

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The complete genome or the genome region containing the two fiber genes of two reference strains and one field isolate representing both serotypes of Fowl adenovirus C were sequenced. Two fiber genes were revealed in the genomes of all three isolates. Fiber 1 and fiber-2 genes of several Fowl adenovirus C isolates were sequenced as well. Both serotypes 4 and 10 have two fiber genes. The genome region containing the fiber gene was also sequenced for the reference strain of Fowl adenovirus B. just one fiber gene was revealed in this strain. Predicted amino acid sequences were compared to already published fiber sequences of different adenovirus isolates and one amino acid substitution within fiber-2 was detected in all of the Fowl adenovirus C isolates that were isolated from chickens with hepatitis-hydropericardium syndrome in comparison to apathogenic isolates. Phylogenetic analyses provided insights about the evolution of fiber genes in avian adenoviruses and their genetic relationships
机译：对包含两个参考菌株的两个纤维基因和一个代表禽腺病毒C血清型的野外分离株的完整基因组或基因组区域进行了测序。在所有三个分离株的基因组中揭示了两个纤维基因。还对几种禽类C分离株的Fiber 1和fiber-2基因进行了测序。血清型4和10都有两个纤维基因。还针对禽腺病毒B的参考菌株对含有纤维基因的基因组区域进行了测序。在该菌株中仅发现了一个纤维基因。将预测的氨基酸序列与已发表的不同腺病毒分离株的纤维序列进行比较，并且与致病性分离株相比，从患有乙型肝炎-心包水综合征的鸡中分离出的所有Fowl腺病毒C分离株中，检测到fibre-2内的一个氨基酸取代。系统发育分析提供了有关禽腺病毒中纤维基因进化及其遗传关系的见解

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