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首页> 外文期刊>Twin research and human genetics : >Physical activity in adolescence as a predictor of alcohol and illicit drug use in early adulthood: a longitudinal population-based twin study.
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Physical activity in adolescence as a predictor of alcohol and illicit drug use in early adulthood: a longitudinal population-based twin study.

机译:青春期的体育活动可预测成年初期酒精和非法药物的使用:一项基于人口的纵向双胞胎研究。

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We investigated prospectively whether physical activity level in adolescence predicts use of alcohol and illicit drugs in early adulthood. We studied 4,240 individual twins (1,870 twin pairs). We classified those who consistently reported frequent leisure physical activity at ages 16, 17 and 181/2 as persistent exercisers, those exercising less than three times monthly as persistently inactive, and all others as occasional exercisers. To control for familial confounds, within-family analyses compared activity-substance use associations in co-twins discordant for baseline physical activity. Individual-based analyses showed no clear association between baseline physical activity and subsequent weekly alcohol consumption. However, weekly alcohol intoxication (OR = 1.9, p = .002) and problems due to alcohol use (OR = 2.0, p < .001) were more common among persistently inactive participants. After excluding those reporting weekly intoxication at baseline, the risk for alcohol intoxication remained elevated among women occasionally (OR = 2.4, p = .017) or persistently (OR = 5.8, p < .001) inactive at baseline, but this association was not replicated within discordant twin pairs. Individual-based analyses showed that drug use in adulthood was more common among those persistently physically inactive in adolescence (OR = 3.7, p < .001) in comparison to those persistently active. This finding was replicated within discordant twin pairs. Among those with no drug experience during adolescence, persistent inactivity (OR = 1.9, p = .007) increased risk for drug use. We conclude that persistent physical inactivity in adolescence may increase the risk of later problems due to excess alcohol use. Sedentary lifestyle predicts illicit drug use even when controlling for familial factors.
机译:我们前瞻性地调查了青少年的体育活动水平是否可以预测成年初期使用酒精和非法药物。我们研究了4,240对双胞胎(1,870对双胞胎)。我们将一直报告在16、17和181/2岁时经常进行休闲体育锻炼的人归为持续锻炼者,每月锻炼次数少于三倍的人为持续不锻炼者,所有其他人为偶尔锻炼者。为了控制家族性混杂症,家庭内部分析比较了双胞胎与基线身体活动不一致的活动-物质使用关联。基于个体的分析显示,基线体育锻炼与随后的每周饮酒之间没有明确的关联。然而,在持续不活动的参与者中,每周酒精中毒(OR = 1.9,p = .002)和因饮酒引起的问题(OR = 2.0,p <.001)更为常见。在排除那些每周报告基线中毒的女性后,酒精中毒的风险在基线时不活跃的女性中偶尔(OR = 2.4,p = .017)或持续性(OR = 5.8,p <.001)仍然较高,但这种关联并非如此在不和谐的双胞胎对中复制。基于个体的分析表明,与持续活跃的青少年相比,在青春期持续缺乏身体活动的青少年(OR = 3.7,p <.001)中成年人使用毒品更为普遍。这一发现在不一致的双胞胎对中重复出现。在青春期期间没有吸毒经历的人中,持续不活动(OR = 1.9,p = .007)会增加吸毒的风险。我们得出的结论是,由于过量饮酒,青春期持续的身体不活动可能会增加以后发生问题的风险。久坐不动的生活方式即使在控制家庭因素的情况下也可以预测非法药物的使用。

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