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首页> 外文期刊>Veterinary Ophthalmology >Effects of low-intensity pulsed ultrasound on wound healing in corneas of dogs following keratoplasty
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Effects of low-intensity pulsed ultrasound on wound healing in corneas of dogs following keratoplasty

机译：低强度脉冲超声对角膜移植术后犬角膜伤口愈合的影响

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The effects of low-intensity pulsed ultrasound on wound healing were evaluated at the graft-cornea transition in dogs following lamellar keratoplasty using tunica vaginalis preserved in 98% glycerin. Twenty-one dogs were subdivided into three groups of seven animals. The first group (W/US) received daily treatment of low-intensity pulsed ultrasound (20 mW/cm(2)) for 15 min for the first 10 days post surgery. The second group (N/US) was submitted to the same procedure but with the ultrasound apparatus turned off. The third group, the control (CO), underwent the surgical procedure only. The animals were clinically evaluated during the initial (1-15 days), intermediate (1630 days) and late (31-120 days) postoperative period. The corneas were evaluated by light microscopy at 1, 3, 7, 15, 30, 60 and 120 days after surgery. Clinically, there were no differences which would promote an advantage to any of the treatments. Light microscopy, however, revealed more extensive vascularization and more advanced wound healing in the W/US group, as well as a tendency towards early graft incorporation. Based on the present results, low-intensity pulsed ultrasound shows advantages, especially in situations where trophic support is a mandatory condition, facilitating better graft incorporation and rapid recovery of stromal organization.
机译：在层状角膜移植术后，使用保存在98％甘油中的阴道膜在犬的角膜移植过渡处评估了低强度脉冲超声对伤口愈合的影响。将二十一条狗细分为三组，每组七只动物。第一组（W / US）在手术后的前10天每天接受低强度脉冲超声（20 mW / cm（2））治疗15分钟。第二组（N / US）接受了相同的操作，但超声仪处于关闭状态。第三组，对照组（CO），仅接受了外科手术。在术后初期（1-15天），中期（1630天）和后期（31-120天）对动物进行临床评估。在手术后1、3、7、15、30、60和120天通过光学显微镜评估角膜。在临床上，没有差异可以促进任何一种治疗的优势。然而，光学显微镜显示，W / US组的血管形成更广泛，伤口愈合更先进，并且有早期移植物掺入的趋势。根据目前的结果，低强度脉冲超声显示出优势，特别是在营养支持是强制性条件的情况下，有利于更好的移植物结合和基质组织的快速恢复。

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