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首页> 外文期刊>Virus Genes >Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008.
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Genetic analysis of the VP1 region of enterovirus 71 reveals the emergence of genotype A in central China in 2008.

机译:对肠道病毒71的VP1区进行的遗传分析显示,在华中地区2008年出现了A型基因型。

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摘要

Enterovirus 71 (EV71) strains from children were characterized by full-length VP1 nucleotide sequencing. Out of 22 clinical specimens, five isolates identified as EV71 were recovered by virus isolation. The VP1 sequences of the five isolates had more than 97.4% sequence identity with prototype virus BrCr, clustering in the genotype A lineage. This represents the first record of genotype A EV71 in China since the BrCr prototype strain was discovered in the USA in 1969.
机译:来自儿童的肠病毒71(EV71)菌株通过全长VP1核苷酸测序进行表征。在22个临床标本中,通过病毒分离回收了5个被鉴定为EV71的分离株。这五个分离株的VP1序列与原型病毒BrCr的序列同一性超过97.4%,聚集在基因型A谱系中。这是自1969年在美国发现BrCr原型菌株以来,在中国的第一个EV71基因型记录。

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