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首页> 外文期刊>The International journal of pharmacy practice >Identifying the key beliefs influencing uptake and adherence to highly active anti-retroviral treatment
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Identifying the key beliefs influencing uptake and adherence to highly active anti-retroviral treatment

机译：确定影响摄取和坚持高效抗逆转录病毒治疗的主要信念

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The advent of highly active anti-retroviral treatment (HAART) revolutionised outcomes in HIV. However, up to one-third of patients decline clinically appropriate treatment recommendations,1 and many do not maintain the high level of adherence that is required for clinical success? Most interventions to facilitate adherence to HAART have focused on removing the practical barriers leading to unintentional non-adherence (e.g. by issuing reminders or dosage aids) These are helpful but are likely to be more effective if they also address perceptual barriers leading to intentional non-adherence. To do this we need a simple framework for eliciting and addressing the key beliefs underpinning patients' decisions to start and continue with treatment. One model that shows promise is the necessity-concerns framework, which has been used to explain non-adherence to medication across several chronic illnesses 3 The aim of this study was to examine the application of the necessity-concerns framework to the problem of suboptimal uptake and adherence to HAART.
机译：高效抗逆转录病毒治疗（HAART）的出现彻底改变了HIV的预后。但是，多达三分之一的患者拒绝接受临床上适当的治疗建议1，而且许多患者不能维持临床成功所需的高依从性吗？大多数促进遵守HAART的干预措施都集中于消除导致无意违背的实际障碍（例如，通过发出提醒或剂量辅助手段）。这些措施很有帮助，但如果它们也解决了导致有意非遵照的知觉障碍，则可能会更有效。坚持。为此，我们需要一个简单的框架来引发和解决支持患者决定开始和继续治疗的关键信念。一种显示希望的模型是必要性关注框架，该模型已用于解释几种慢性病对药物的不依从性3这项研究的目的是研究必要性关注框架在亚最佳摄取问题上的应用并遵守HAART。

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