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首页> 外文期刊>The International journal of pharmacy practice >Management of long-term hypothyroidism: A potential marker of quality of medicines reconciliation in the intensive care unit
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Management of long-term hypothyroidism: A potential marker of quality of medicines reconciliation in the intensive care unit

机译：长期甲状腺功能减退症的管理：重症监护室药物和解质量的潜在标志

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Objective Significant errors can be made during medication prescribing, dispensing and administration. One source of error and potential for harm is unintentional omission. Medicines reconciliation seeks to reduce the impact of this between transfer of care. In long-term hypothyroidism, patients are dependent upon levothyroxine and there are few contraindications to its prescription. We considered levothyroxine prescription in long-term hypothyroidism as a marker of medicines reconciliation on admission and during stay in the intensive care unit (ICU). Methods: A retrospective chart review was undertaken in a tertiary referral university ICU with all patients who were receiving long-term levothyroxine therapy identified. Notes were reviewed for the presence of thyroid-replacement prescription and for thyroid function tests, in addition to demographic, length of stay and mortality data. Key findings Thyroid-replacement therapy was not prescribed for more than 7 days in 23/133 (17.3%) patients and omitted entirely in three patients. A further 28/133 (21.1%) patients were intolerant of enteral feeding for more than 7 days and were thus unable to have oral levothyroxine administered. None of these patients received parenteral therapy. Thyroid function tests were performed in 104/133 (78.2%) patients. Conclusions: Prescription of chronic therapy, in this case thyroid-replacement therapy, was inadequate. This highlights the need for a progressive medicines-reconciliation process embedded within the daily ICU programme. IJPP
机译：目的在开药，配药和给药过程中可能会发生重大错误。错误和潜在危害的来源之一是无意遗漏。药品和解旨在减少这种转移之间的影响。在长期甲状腺功能减退症中，患者依赖左甲状腺素治疗，其处方禁忌症很少。我们认为长期甲状腺功能减退症中的左甲状腺素处方药是入院时和在重症监护病房（ICU）期间药物调和的标志。方法：在一家转诊大学的重症监护病房（ICU）中进行回顾性图表审查，确定所有接受长期左甲状腺素治疗的患者。除人口统计资料，住院时间和死亡率数据外，还对注释的甲状腺替代处方和甲状腺功能检查进行了审查。重要发现23/133（17.3％）患者未超过7天开甲状腺替代疗法，三例患者完全取消。另有28/133（21.1％）的患者不能接受7天以上的肠内喂养，因此无法口服左旋甲状腺素。这些患者均未接受肠胃外治疗。 104/133（78.2％）患者进行了甲状腺功能检查。结论：长期治疗的处方不足，在这种情况下为甲状腺替代治疗。这突显了在ICU日常计划中嵌入渐进式药物和解程序的必要性。联合会

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