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Drug selection for formulary inclusion using modified system of objectified judgment analysis (SOJA) methodology

机译:使用改进的客观判断分析系统(SOJA)方法选择处方药

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The National Health Service expenditure on medicines is increasing at 14% per year.1 Even with a pharmaceutical price regulation scheme in place, medicine prices in the UK are now the highest in Europe and parallel import trading has increased considerably (estimated cost to industry: ,,4bn per year).2 There is increasing concern over drug selection, motivated by the introduction of new expensive drugs, cost-cutting pressures and the need to improve quality of care. Restricted formularies are increasingly used to help contain costs. Over the last 10 years Janknegt and colleagues in The Netherlands have developed a method of drug selection for hospital formulary inclusion: the system of objectified judgment analysis (SOJA).3 Their one-step method evaluates a specific drug class for the treatment of one indication e.g. diuretics for hypertension; selection criteria (including cost) are prospectively defined and weighted, and drugs within the selected class are then scored for each criterion,. The aim of this study was to develop a modification of the SOJA approach to select appropriate product lines of angiotensin-con-verting enzyme inhibitors (ACEIs), across all licensed indications,,, for inclusion in a joint formulary, covering both primary and secondary care, within a health board in Northern Ireland.
机译:国家卫生服务局(National Health Service)在药品上的支出每年以14%的速度增长。1即使制定了药品价格监管计划,英国的药品价格现在仍是欧洲最高的,并且平行进口贸易已大大增加(行业的估计成本:每年,约40亿欧元)。2人们对药物的选择越来越关注,这是由于引入了新的昂贵药物,削减成本的压力以及提高护理质量的需要。越来越多地使用受限配方来控制成本。在过去的十年中,荷兰的Janknegt及其同事开发了一种用于医院处方纳入的药物选择方法:客观判断分析系统(SOJA)。3他们的一步法评估了用于治疗一种适应症的特定药物类别例如利尿剂治疗高血压;对选择标准(包括成本)进行前瞻性定义和加权,然后针对每个标准对所选类别中的药物进行评分。这项研究的目的是对SOJA方法进行改进,以在所有许可的适应症中选择合适的血管紧张素转换酶抑制剂(ACEI)产品系列,以包括在联合配方中,涵盖初级和次级护理,在北爱尔兰的卫生局内。

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