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首页> 外文期刊>The International journal of pharmacy practice >UK interventions to control medicines wastage: a critical review
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UK interventions to control medicines wastage: a critical review

机译：英国控制药物浪费的干预措施：一项重要评论

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Objective The objective is to evaluate the scope of medicines wastage in the UK, assigning a value to the costs at both a national and individual patient level to assess the cost-effectiveness of the pharmacy interventions that have been introduced to curb wastage. Methods Publicly available information was assessed in a desk-based systematic review using online search engines and publication databases. Data on community prescribing trends and costs in England from 1997 to 2008 from the Department of Health, and published reports from Primary Care Trusts (PCTs) comprise the core information that has been analysed. Key findings The commonly used upper wastage estimate of 10% is likely to be overstated, because it pre-dates major measures to curb wastage and over-prescribing. In pilot programmes, medicines use reviews have achieved cost savings of up to 20%. Awareness campaigns aimed at patients appear to be effective. Twenty-eight-day repeat prescribing has resulted in year-on-year reductions on the quantity of medication issued per prescription item to reach an average prescription length of 40 days in 2008. The increasing availability of generic medications has seen significant reductions in net ingredient costs. Nearly two-thirds of prescriptions are now issued as generics, with an average net ingredient cost of ?83. Pharmacy charges to dispense a prescription item in 2008 averaged ?81, so that pharmacy charges make up around one-third of the cost of most prescription items dispensed. If all 842.5 million prescription items issued by the NHS in England in 2008 had been 28-day repeat-dispensing items, this would have added a projected ?0 million to the actual pharmacy costs of around ?5 billion. Conclusions Unnecessary spending on pharmacy charges has the potential to outstrip the estimated cost of medicines wastage in the UK. The cost-effectiveness of restricted prescription lengths for the cheaper, mostly generic medications merits an urgent re-examination.
机译：目的目的是评估英国药物浪费的范围，为国家和个人患者水平的费用分配一个值，以评估为遏制浪费而采用的药物干预措施的成本效益。方法使用在线搜索引擎和出版物数据库，在基于案头的系统评价中评估可公开获得的信息。卫生部提供的有关1997年至2008年英格兰社区处方趋势和费用的数据，以及基层医疗信托（PCT）发布的报告构成了已分析的核心信息。主要发现常用的10％的浪费上限估计可能被夸大了，因为它早于遏制浪费和过度开处方的主要措施。在试点计划中，药品使用审查已节省了高达20％的成本。针对患者的宣传运动似乎是有效的。 28天的重复开处方导致每个处方项目发行的药物数量同比减少，到2008年平均处方时长达到40天。通用药物供应的增加使净成分显着减少费用。现在，将近三分之二的处方药是仿制药，平均净成分成本为83英镑。 2008年，配发处方药的药房费用平均为81英镑，因此药房费用约占大多数配药费用的三分之一。如果英国国家医疗服务体系（NHS）在2008年发布的所有8.425亿处方药都是28天的重复分发药，那么实际药房成本约为50亿欧元，这将使预算增加0万欧元。结论在英国，不必要的药房费用支出有可能超过估计的药物浪费成本。对于较便宜的，大多为非专利药品的有限处方时长的成本效益值得紧急重新检查。

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