The evolution simulation of zinc finger domain sequence—Application of genetic algorithms in protein structure study

SUN Zhirong; HAN Hao

首页> 外文期刊>Chinese science bulletin >The evolution simulation of zinc finger domain sequence—Application of genetic algorithms in protein structure study

【24h】

The evolution simulation of zinc finger domain sequence—Application of genetic algorithms in protein structure study

机译：锌指结构域序列的进化模拟—遗传算法在蛋白质结构研究中的应用

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

GENETIC algorithms are very efficient search mechanisms. The application of genetic algorithms in the protein structure study provides not only a convenience algorithm for the search of the lowest energy status (according to the thermodynamics theory,the natural protein has the lowest energy status), but a new kind of research method. Some potential zinc finger primary structure is evoluted from animo acid sequences generated randomly. The work in this note not only gives some evidence for the random origin of amino acid sequence, but investigates the ability of genetic algorithms to search vast conformational spaces.

机译：GENETIC算法是非常有效的搜索机制。遗传算法在蛋白质结构研究中的应用不仅为寻找最低能量状态（根据热力学理论，天然蛋白质具有最低能量状态）提供了一种方便的算法，而且提供了一种新的研究方法。一些潜在的锌指一级结构是从随机产生的苯胺酸序列进化而来的。本文中的工作不仅为氨基酸序列的随机起源提供了一些证据，而且还研究了遗传算法搜索巨大构象空间的能力。

著录项

来源
《Chinese science bulletin》 |1997年第22期|共4页
作者
SUN Zhirong; HAN Hao;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类自然科学现状及发展;
关键词
genetic algorithm; zinc finger domain; evolution simulation; protein sequence;

机译：遗传算法;锌指域;进化模拟;蛋白质序列;

相似文献

外文文献
中文文献
专利

1. The evolution simulation of zinc finger domain sequence—Application of genetic algorithms in protein structure study [J] . SUN Zhirong, HAN Hao Chinese science bulletin . 1997,第22期

机译：锌指结构域序列的进化模拟—遗传算法在蛋白质结构研究中的应用
2. Phylogenetic distribution and evolution of the linked RNA-binding and NOT1-binding domains in the tristetraprolin family of tandem CCCH zinc finger proteins [J] . BlackshearP.J., PereraL. Journal of interferon and cytokine research: The official journal of the International Society for Interferon and Cytokine Research . 2014,第4期

机译：串联CCCH锌指蛋白的tristetraprolin家族中连接的RNA结合和NOT1结合域的系统发生分布和进化
3. Role of protein structure and the role of individual fingers in zinc finger protein-DNA recognition: a molecular dynamics simulation study and free energy calculations [J] . Hamed Mazen Y. Journal of Computer-Aided Molecular Design . 2018,第6期

机译：蛋白质结构的作用及单个手指在锌指蛋白-DNA识别中的作用：分子动力学模拟研究和自由能计算
4. Fuzzy sequence pattern matching in zinc finger domain proteins [C] . Chang, B.C.H., Halgamuge, IFSA World Congress and 20th NAFIPS International Conference, 2001. Joint 9th . 2001

机译：锌指结构域蛋白中的模糊序列模式匹配
5. New Vistas in Zinc Finger Biochemistry: Examining the Metal-Mediated DNA Recognition of the Neural Zinc Finger Factor/Myelin Transcription Factor Family of Non-Classical Zinc Finger Proteins and Creating Catalytic Moieties from Zinc Finger Scaffolds [D] . Besold, Angelique N. 2014

机译：锌指生物化学的新视野：检查非经典锌指蛋白的神经锌指因子/髓鞘转录因子家族的金属介导的DNA识别，并从锌指支架中产生催化部分
6. Phylogenetic Distribution and Evolution of the Linked RNA-Binding and NOT1-Binding Domains in the Tristetraprolin Family of Tandem CCCH Zinc Finger Proteins [O] . Perry J. Blackshear, Lalith Perera -1

机译：串联CCCH锌指蛋白的Tristetraprolin家族中连锁的RNA结合和NOT1结合域的系统发生分布和进化。
7. Phylogenetic Distribution and Evolution of the Linked RNA-Binding and NOT1-Binding Domains in the Tristetraprolin Family of Tandem CCCH Zinc Finger Proteins [O] . Perry J. Blackshear, Lalith Perera 2014

机译：Tristetraproolin串联锌指蛋白三胞嘧啶系列连接的RNA结合和Not1结合结构域的系统发育分布及演化

The evolution simulation of zinc finger domain sequence—Application of genetic algorithms in protein structure study

摘要

著录项

相似文献

相关主题

期刊订阅