Monte Carlo simulation on coordinated movement of kinesin and dynein motors

Wang H; Dou SX; Wang PY

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Monte Carlo simulation on coordinated movement of kinesin and dynein motors

机译：动力蛋白和达因电机协调运动的蒙特卡洛模拟

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Kinesin and dynein are two important classes of molecular motors which are responsible for active organelle tracking and cell division. They can work together to carry a cargo, moving along the microtubule in a coordinated way. We use Monte Carlo method to simulate the dynamics of this coordinated movement. Based on four essential assumptions, our simulations reproduce some features of the recent in vivo experiments. The fast moving speed of the cargo is simulated and the speed distribution is presented.

机译：驱动蛋白和动力蛋白是分子运动的两个重要类别，它们负责主动细胞器追踪和细胞分裂。他们可以一起运送货物，以协调的方式沿着微管移动。我们使用蒙特卡洛方法来模拟这种协调运动的动力学。基于四个基本假设，我们的模拟重现了近期体内实验的某些功能。模拟了货物的快速移动速度并给出了速度分布。

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《Chinese physics letters》 |2008年第1期|共4页
作者
Wang H; Dou SX; Wang PY;
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原文格式 PDF
正文语种 eng
中图分类物理学;
关键词
HAND-OVER-HAND; CYTOPLASMIC DYNEIN; ATP HYDROLYSIS; IN-VIVO; TRANSPORT; MECHANICS; PROTEINS; MODEL; LOAD;

机译：双手操作;细胞膜动力学;ATP水解;体内;运输;力学;蛋白质;模型;负载;

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专利

1. Monte Carlo simulation on coordinated movement of kinesin and dynein motors [J] . Wang H, Dou SX, Wang PY Chinese physics letters . 2008,第1期

机译：动力蛋白和达因电机协调运动的蒙特卡洛模拟
2. Monte Carlo Simulation of Kinesin Movement with a Lattice Model [J] . WANG Hong, DOU Shuo-Xing, WANG Peng-Ye 中国物理快报：英文版 . 2005,第011期

机译：格子模型驱动蛋白运动的蒙特卡罗模拟
3. Kinesin and dynein move a peroxisome in vivo: A tug-of-war or coordinated movement? [J] . Kural C, Kim H, Syed S, Science . 2005,第5727期

机译：驱动蛋白和动力蛋白在体内移动一个过氧化物酶：拔河运动还是协调运动？
4. Performance Analysis of a Reduced Data Movement Algorithm for Neutron Cross Section Data in Monte Carlo Simulations [C] . John R. Tramm, Andrew R. Siegel, Benoit Forget, International Conference on Exascale Applications and Software . 2015

机译：蒙特卡罗模拟中中子截面数据减少数据移动算法的性能分析
5. UNC-83 coordinates kinesin-1 and dynein to move the nucleus along dynamic, polarized microtubules. [D] . Fridolfsson, Heidi Nicole. 2010

机译：UNC-83协调kinesin-1和dynein沿动态极化的微管移动核。
6. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations. [O] . Yi-der Chen, Bo Yan, Robert J Rubin 2002

机译：单个夹紧因子驱动的磁珠在强制钳位的运动分析中的波动和运动随机性：蒙特卡洛模拟。
7. Fluctuations and randomness of movement of the bead powered by a single kinesin molecule in a force-clamped motility assay: Monte Carlo simulations. [O] . Chen, Yi-der, Yan, Bo, Rubin, Robert J 2002

机译：单个夹紧因子驱动的磁珠在强制钳位的运动分析中的波动和运动随机性：蒙特卡洛模拟。

Monte Carlo simulation on coordinated movement of kinesin and dynein motors

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