Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed

FENG Dan; ZENG Zonghao

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Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed

机译：晶体中蛋白质-蛋白质界面的统计分析：特定和非特定的界面差异分布

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The distribution of contact areas, or fractions of contacting, of protein-protein interfaces in crystals of pure polypcptides contains two components: a major exponential distribution and a minor flatter distribution. Suppose the two components belongto specific and non-specific contacts, respectively, then the probability of a contact with a given area, or fraction of contacting, can he estimated. By dividing the whole database into two sub-databases, one of them is known to contain more specific contacts than the other, this hypothesis is confirmed and it is also proved that the fraction of contacting is more effective than the contact area on discriminating specific and non-specific contacts in protein crystals.

机译：纯多肽晶体中蛋白质-蛋白质界面的接触面积或接触分数的分布包含两个成分：主要的指数分布和次要的平坦分布。假设这两个分量分别属于特定和非特定接触，则可以估计与给定区域或部分接触的概率。通过将整个数据库划分为两个子数据库，已知其中一个子数据库比另一个子数据库包含更多的特定联系人，这一假设得到了证实，并且还证明了在区分特定和特定子类别时，联系的部分比联系区域更有效。蛋白质晶体中的非特异性接触。

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《Chinese science bulletin》 |2004年第3期|共4页
作者
FENG Dan; ZENG Zonghao;
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原文格式 PDF
正文语种 eng
中图分类自然科学现状及发展;
关键词
crystal structure; prolein-protein interface; statistical analysis; specific interlace; protein oligomer;

机译：晶体结构;蛋白-蛋白质界面;统计分析;特异性交织;蛋白质低聚物;

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专利

1. Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed [J] . FENG Dan, ZENG Zonghao Chinese science bulletin . 2004,第3期

机译：晶体中蛋白质-蛋白质界面的统计分析：特定和非特定的界面差异分布
2. Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed [J] . FENG Dan, ZENG Zonghao Chinese science bulletin . 2004,第3期

机译：晶体中蛋白质-蛋白质界面的统计分析：特定和非特定的界面差异分布
3. Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed [J] . FENG Dan, ZENG Zonghao Chinese science bulletin . 2004,第3期

机译：晶体中蛋白质-蛋白质界面的统计分析：特定和非特定的界面差异分布
4. Non-specific and specific cellular responses on the supramolecular bio-interface with mobile substances [C] . Sachiro Kakinoki, Ji-Hun Seo, Atsushi Yamashita, World biomaterials congress . 2012

机译：超分子生物界面上与移动物质的非特异性和特异性细胞反应
5. Predicting protein-protein interactions and their interacting interfaces with statistical learning techniques. [D] . Gonzalez, Alvaro J. 2012

机译：用统计学习技术预测蛋白质相互作用。
6. Studies of protein-protein interfaces: a statistical analysis of the hydrophobic effect. [O] . C. J. Tsai, S. L. Lin, H. J. Wolfson, 1997

机译：蛋白质-蛋白质界面研究：疏水作用的统计分析。
7. Studies of protein-protein interfaces: a statistical analysis of the hydrophobic effect. [O] . Tsai, C. J., Lin, S. L., Wolfson, H. J., 2008

机译：蛋白质-蛋白质界面研究：疏水作用的统计分析。
8. Determination of Specific Adsorption of Some Simple Anions at a Polycrystalline Silver-Aqueous Interface Using Differential Capacitance and Kinetic Probe Techniques. [R] . Larkin, D., Guyer, K. L., Hupp, J. T., 1982

机译：用差分电容和动力学探针技术测定多晶银 - 水界面中某些简单阴离子的比吸附。

Statistical analysis on protein-protein interface in crystals: Specific and non-specific interfaces are differentially distributed

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