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Thindown in biological 1-hit detectors: E. Coli B/r and Bs-1

机译:生物一击检测器的细化:大肠杆菌B / r和Bs-1

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According to the theory of Butts and Katz and the new radial dose distribution of Zhang et al., we have calculated inactivation cross sections for the heavy ion bombardment of E Coli B/r and Bs-1 which was in agreement with the measurements of ScHaferet al., made with ions from O to U at energies from 1,5 to 19,5 MeV/u. The data display "thindown", and the decrease in cross section with an increase in stopping power is accompanied by a decrease in energy of a bombarding ion, Following an earlier analysis of heavy ion bombardments of these E. Coli mutants with low atomic number ions at energies neighboring 10 MeV/u by Katz and Zachariah, it can be seen that these bacteria act as 1-hit detectors on the response of these bacteria to ions of lower atomic number and LET where thindown is not exhibited. The analysis of thindown in these bacteria is much clearer than that in the case of mammalian cells because of the relative simplicity of the structure of these bacteria as compared to the complexity ofmammalian cell structure. The significance of studying the thindown of E. Coli is to get further understanding of the radiation action in biology.
机译:根据Butts和Katz的理论以及Zhang等人的新的径向剂量分布,我们计算了E Coli B / r和Bs-1的重离子轰击的失活截面,这与ScHaferet的测量结果一致由O到U的离子以1.5 MeV / u的能量制成。在较早地分析了这些低原子序数的大肠杆菌突变体的重离子轰击之后,数据显示“变薄”,并且随着阻止能力的增加,横截面的减小伴随着轰击离子能量的降低。在Katz和Zachariah的能量接近10 MeV / u的能量下,可以看出,这些细菌对这些细菌对较低原子序数的离子和LET的响应(未表现出稀薄性)充当1-hit检测器。由于与哺乳动物细胞结构的复杂性相比,这些细菌的结构相对简单,因此与哺乳动物细胞相比,这些细菌的稀疏分析要清晰得多。研究大肠杆菌稀薄度的意义在于进一步了解生物学中的辐射作用。

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