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首页> 外文期刊>Chemotherapy: International Journal of Experimental and Clinical Chemotherapy >A 13-year study of antimicrobial susceptibility of common gram-negative bacteria isolated from the bloodstream in a teaching hospital.
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A 13-year study of antimicrobial susceptibility of common gram-negative bacteria isolated from the bloodstream in a teaching hospital.

机译：在一家教学医院，对从血液中分离出的常见革兰氏阴性细菌的抗菌药敏感性进行了为期13年的研究。

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摘要

The choice of antimicrobial therapy for the treatment of bacteremia is often empirical and based on the knowledge of susceptibility profiles of the most common bacteria. We analyzed blood culture isolates from a teaching hospital for 13 years prospectively. This study examined the susceptibility profiles of 6,616 gram-negative bacteria. Escherichia coli ranked among the commonest bacteria, representing 43.6% (2,890) of all gram-negative isolates. Klebsiella sp. ranked second, 17.7% (1,171) and 16.7% were resistant to ceftazidime in 1997. There was a trend towards an increase in resistance to fluoroquinolones in the common gram-negative bacteria. Imipenem was the most active agent against gram-negative bacteria. The results of the susceptibility of gram-negative bacteria causing bacteremia provide valuable information for implementing the appropriate chemotherapy for bacteremia. Copyright 1999 S. Karger AG, Basel
机译：抗菌素治疗菌血症的治疗方法的选择通常是经验性的，并且基于对最常见细菌的药敏性的了解。我们对一家教学医院的血液培养分离株进行了13年的前瞻性分析。这项研究检查了6,616克阴性细菌的敏感性。大肠埃希菌是最常见的细菌，占所有革兰氏阴性菌的43.6％（2,890）。克雷伯菌排在第二位的是1997年对头孢他啶的耐药性为17.7％（1,171）和16.7％。在常见的革兰氏阴性细菌中，对氟喹诺酮类药物的耐药性呈增加趋势。亚胺培南是对抗革兰氏阴性菌最活跃的药物。革兰氏阴性细菌引起菌血症的敏感性结果为实施适当的菌血症化学疗法提供了有价值的信息。版权所有1999 S.Karger AG，巴塞尔

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