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Autoimmune hepatitis: 50 years of (slow) progress

机译:自身免疫性肝炎:50年(缓慢)进展

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摘要

In general, PG is also associated with the administration of drugs such as granulocyte colony-stimulating factor,10 antipsychotic agents and IFN-a.Indeed, IFN-oc treatment has some well-known cutaneous side-effects such as dry skin, hair loss and vitiligo. Furthermore, cutaneous ulcerations, indurated erythema and leukocy-toclastic vasculitis may occur at IFN-a injection sites. The pathogenesis of local cutaneous reactions against IFN-a is still unknown. Several case reports have suggested that PG results from IFN-a treatment during the course of hematological malignancies.
机译:通常,PG也与诸如粒细胞集落刺激因子,10种抗精神病药和IFN-α等药物的给药有关。事实上,IFN-oc治疗具有一些众所周知的皮肤副作用,例如皮肤干燥,脱发和白癜风。此外,在IFN-α注射部位可能发生皮肤溃疡,硬结性红斑和白细胞弹力性血管炎。针对IFN-α的局部皮肤反应的发病机制仍然未知。几例病例报告提示,PG在血液恶性肿瘤过程中是由IFN-α治疗引起的。

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