• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Human Reproduction >Selection of the optimal day for oocyte retrieval based on the diameter of the dominant follicle in hCG-primed in vitro maturation cycles.
【24h】

Selection of the optimal day for oocyte retrieval based on the diameter of the dominant follicle in hCG-primed in vitro maturation cycles.

机译：根据hCG启动的体外成熟周期中优势卵泡的直径，选择最佳的卵母细胞回收日。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: The efficiency of in vitro maturation (IVM) techniques is suboptimal compared with controlled ovarian stimulation combined with IVF cycles, and studies are needed to identify factors that predispose IVM cycles to success or failure. We compared the outcome of IVM cycles with different dominant follicle (DF) size at oocyte retrieval following hCG priming. METHODS: IVM was performed in 160 patients with polycystic ovaries (171 cycles). We administered 10,000 IU hCG s.c. 35-38 h before oocyte collection when endometrial thickness reached at least 6 mm. IVM cycles were retrospectively analyzed according to DF diameter as follows; Group 1: DF diameter 14 mm. RESULTS A positive correlation was observed between DF size and number of in vivo matured oocytes collected (Group 1, 2 and 3 = 6.9, 10.6 and 15.1%, respectively). The rates of IVM, fertilization and embryo development were similar among the sibling immature oocytes collected from the threegroups. However, clinical pregnancy rate in Group 2 (40.3%) was higher than Group 3 (17.1%) (P < 0.05). Moreover, implantation rates in Groups 1 (13.6%) and 2 (14.3%) were higher than Group 3 (4.9%) (P < 0.01). CONCLUSIONS: Our results suggest that oocyte collection in IVM cycles should be performed when the DF is 14 mm diameter or less. Sibling immature oocytes may be affected detrimentally if a DF >14 mm is present at oocyte collection.
机译：背景：体外成熟（IVM）技术的效率与结合IVF周期的受控制的卵巢刺激相比是次优的，并且需要进行研究以识别导致IVM周期成败的因素。我们比较了hCG启动后卵母细胞取回时具有不同优势卵泡（DF）大小的IVM周期的结果。方法：对160例多囊卵巢患者（171个周期）进行了IVM。我们管理了10,000 IU hCG s.c.收集卵母细胞前35-38 h，子宫内膜厚度至少达到6 mm。根据DF直径对IVM周期进行回顾性分析，方法如下：第1组：DF直径<或= 10 mm，第2组：10至14 mm，第3组：> 14 mm。结果观察到DF大小与收集的体内成熟卵母细胞数量呈正相关（第1组，第2组和第3组分别为6.9％，10.6％和15.1％）。从三组中收集的同胞未成熟卵母细胞中，IVM，受精和胚胎发育的速率相似。但是，第二组的临床妊娠率（40.3％）高于第三组（17.1％）（P <0.05）。此外，第1组（13.6％）和第2组（14.3％）的植入率高于第3组（4.9％）（P ＜0.01）。结论：我们的结果表明，当DF直径为14 mm或更小时，应在IVM周期中收集卵母细胞。如果在卵母细胞收集中存在DF> 14 mm，则同胞未成熟卵母细胞可能受到不利影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号