Study on chemical constituents and cytotoxic activities of salacia chinensis growing in vietnam

Minh T.T.; Anh N.T.H.; Thang V.D.; Sung T.V.

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Study on chemical constituents and cytotoxic activities of salacia chinensis growing in vietnam

机译：越南Salacia chinensis的化学成分和细胞毒活性研究

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Two new triterpenoids, named 7α,21α-dihydroxyfriedelane-3-one (1) and 7α,29-dihydroxyfriedelane- 3-one (2) have been isolated from the ethyl acetate extract of the stems of Salacia chinensis besides the known triterpenoid 21α,30-dihydroxyfriedelane-3-one (3). The structures of the isolated compounds were elucidated on the basis of spectral analysis. Eight triterpenoids from this plant have been tested against the four cancer cell lines Hep-G2, LU, KB, and MCF-7. The new compound 1 showed good activity against all four tested cell lines.

机译：除了已知的三萜类化合物21α外，还从中华ala草茎的乙酸乙酯提取物中分离出了两种新的三萜类化合物，分别名为7α，21α-dihydroxyfriedelane-3-one（1）和7α，29-dihydroxyfriedelane-3-one（2）。 30-二羟基苯并戊烷-3-一（3）。在光谱分析的基础上阐明了分离的化合物的结构。来自该植物的八种三萜类化合物已针对四种癌细胞系Hep-G2，LU，KB和MCF-7进行了测试。新化合物1对所有四个测试细胞系均显示出良好的活性。

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《Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences》 |2010年第10期|共5页
作者
Minh T.T.; Anh N.T.H.; Thang V.D.; Sung T.V.;
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正文语种 eng
中图分类化学;
关键词
Cytotoxic activities; Salacia chinensis; Triterpenes;

机译：细胞毒活性;中华ala;三萜;

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1. Study on chemical constituents and cytotoxic activities of salacia chinensis growing in vietnam [J] . Minh T.T., Anh N.T.H., Thang V.D., Zeitschrift fur Naturforschung, B. A Journal of Chemical Sciences . 2010,第10期

机译：越南Salacia chinensis的化学成分和细胞毒活性研究
2. Natural Antidiabetic Potential of Salacia chinensis L. (Celastraceae) Based on Morphological, Phytochemical, Physico-chemical and Bioactivity: A Promising Alternative for Salacia reticulata Thw [J] . Keeragalaarachchi K.A.G.P., R.M. Dharmadasa, Wijesekara R.G.S., World Journal of Agricultural Research . 2016,第2期

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3. A Comparative Study of Chemical Constituents and Antimicrobial Activity of Essential Oil of Litchi chinensis Growing in Different Geographical Areas of India [J] . Rawat Preeti, Azad Arpit, Kumar Anil, Journal of Essential Oil-Bearing Plants . 2017,第6期

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Study on chemical constituents and cytotoxic activities of salacia chinensis growing in vietnam

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