Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration

Kunzi V; Klap JM; Seiberling MK; Herzog C; Hartmann K; Kursteiner O; Kompier R; Grimaldi R; Goudsmit J

首页> 外文期刊>Vaccine >Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration

【24h】

Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration

机译：与肌肉内全剂量给药相比，皮内注射低剂量病毒体佐剂型流感疫苗的免疫原性和安全性

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

BACKGROUND: Despite the established benefit of intramuscular (i.m.) influenza vaccination, new adjuvants and delivery methods for comparable or improved immunogenicity are being explored. Intradermal (i.d.) antigen administration is hypothesized to initiate an efficient immune response at reduced antigen doses similar to that observed after i.m. full dose vaccination. METHODS: In a randomized, partially blinded phase II study 224, healthy adults aged >/=18 to

机译：背景：尽管肌内（i.m.）流感疫苗接种具有确定的益处，但仍在探索新的佐剂和可比较或改善的免疫原性的递送方法。假定皮内（i.d.）抗原施用以降低的抗原剂量启动有效的免疫反应，该剂量与在i.m.之后观察到的相似。全剂量疫苗接种。方法：在一项随机，部分不知情的II期研究224中，年龄≥/ = 18至

著录项

来源
《Vaccine》 |2009年第27期|共7页
作者
Kunzi V; Klap JM; Seiberling MK; Herzog C; Hartmann K; Kursteiner O; Kompier R; Grimaldi R; Goudsmit J;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类预防医学、卫生学;
关键词

相似文献

外文文献
中文文献
专利

1. Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration [J] . Kunzi V, Klap JM, Seiberling MK, Vaccine . 2009,第27期

机译：与肌肉内全剂量给药相比，皮内注射低剂量病毒体佐剂型流感疫苗的免疫原性和安全性
2. A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59~R-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [J] . Giovanni Delia Cioppa, Uwe Nicolay, Kelly Lindert Human vaccines . 2014,第6期

机译：一项针对老年人的剂量范围研究，比较了皮内和肌肉内注射MF59〜R佐剂和非佐剂的季节性流感疫苗的安全性和免疫原性
3. A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59 (R)-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [J] . Della Cioppa Giovanni, Nicolay Uwe, Lindert Kelly, Human vaccines & immunotherapeutics. . 2014,第6期

机译：一项针对老年人的剂量范围研究，比较了在皮内和肌肉内施用MF59（R）佐剂和非佐剂的季节性流感疫苗的安全性和免疫原性
4. Dose sparing of influenza virus-like particle vaccine administered to the skin using microneedles [C] . Yeu-Chun Kim, Fu-Shi Quan, Richard W. Compans, Annual meeting exposition of the Controlled Release Society . 2011

机译：使用微针向皮肤施用流感病毒样颗粒疫苗的剂量节约
5. Effects of continuous administration of low-dose of Escherichia coli lipopolysaccharide in chicks and poults fed non toxic doses of aflatoxin B1 and T-2 toxin. [D] . Guaiume, Elisangela Aparecida. 2005

机译：小剂量连续饲喂无毒黄曲霉毒素B1和T-2毒素的雏鸡和家禽大肠杆菌脂多糖的效果。
6. A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [O] . Giovanni Della Cioppa, Uwe Nicolay, Kelly Lindert, 2014

机译：一项针对老年人的剂量范围研究比较了在皮内和肌肉内施用MF59®佐剂和非佐剂的季节性流感疫苗的安全性和免疫原性
7. A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [O] . Della Cioppa Giovanni, Nicolay Uwe, Lindert Kelly, 2014

机译：一项针对老年人的剂量范围研究，比较皮内和肌内给药后mF59®-佐剂和非佐剂季节性流感疫苗的安全性和免疫原性特征

Immunogenicity and safety of low dose virosomal adjuvanted influenza vaccine administered intradermally compared to intramuscular full dose administration

摘要

著录项

相似文献

相关主题

期刊订阅