Echinacea purpurea aerial extract alters course of influenza infection in mice

Fusco Dahlene; Liu Xinyan; Savage Caroline; Taur Ying; Xiao Weilie; Kennelly Edward; Yuan Jianda; Cassileth Barrie; Salvatore Mirella; Papanicolaou Genovefa A.

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Echinacea purpurea aerial extract alters course of influenza infection in mice

机译：紫锥菊紫胶空中提取物改变小鼠流感感染的过程

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Influenza infection is a major clinical problem and Echinacea purpurea, a widely consumed botanical product, is purported to alter the course of respiratory infections including influenza. Mice infected with WSN influenza A and treated with E. purpurea polysaccharide extract had less weight loss than untreated mice but similar pulmonary viral titers. Echinacea-treated mice had lower systemic and pulmonary KC and IL-10 levels and lower systemic IFN-gamma levels following influenza infection. These suggest that E. purpurea alters the clinical course of influenza infection in mice through modulation of cytokines and not direct antiviral activity.

机译：流行性感冒是一个主要的临床问题，据称紫锥菊是一种广泛消费的植物产品，据称可以改变包括流感在内的呼吸道感染的病程。与未经处理的小鼠相比，感染了WSN甲型WSN流感病毒并经紫癜大肠杆菌多糖提取物治疗的小鼠体重减轻较少，但肺病毒滴度相似。紫锥菊治疗的小鼠在感染流感后具有较低的全身和肺KC和IL-10水平以及较低的全身IFN-γ水平。这些表明紫癜大肠杆菌通过调节细胞因子而不是直接的抗病毒活性来改变小鼠流感感染的临床过程。

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《Vaccine》 |2010年第23期|共7页
作者
Fusco Dahlene; Liu Xinyan; Savage Caroline; Taur Ying; Xiao Weilie; Kennelly Edward; Yuan Jianda; Cassileth Barrie; Salvatore Mirella; Papanicolaou Genovefa A.;
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正文语种 eng
中图分类医学免疫学;
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disease type;

机译：疾病类型;

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1. Echinacea purpurea aerial extract alters course of influenza infection in mice [J] . Fusco Dahlene, Liu Xinyan, Savage Caroline, Vaccine . 2010,第23期

机译：紫锥菊紫胶空中提取物改变小鼠流感感染的过程
2. Antiviral activity of the Echinacea purpurea extract Echinaforce (R) against the highly pathogenic avian influenza virus (H7N9) [J] . Schoop R., Stephan P., Suter A. Planta medica: Natural products and medicinal plant research . 2015,第16期

机译：紫锥菊提取物Echinaforce（R）对高致病性禽流感病毒（H7N9）的抗病毒活性
3. Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian Influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV) [J] . Stephan Pleschka, Michael Stein, Roland Schoop, Virology Journal . 2009,第1期

机译：紫锥菊标准提取物对高致病性禽流感病毒（H5N1，H7N7）和猪源性H1N1（S-OIV）的抗病毒特性和作用方式
4. Anti-Newcastle Disease Virus Effects of Echinacea Purpurea Formula in vitro and in vivo: Anti-Newcastle Disease Effects of Echinacea Purpurea Formula [C] . Shi-Ning Guo, Xue-Lian Tang, Da-You Shi, International Conference on Remote Sensing, Environment and Transportation Engineering . 2011

机译：Echinacea purpurea公式在体外和体内抗染料疾病病毒效应：抗纽卡斯尔疾病的抗染素疾病症状
5. A comparison of both water and ethanol extracts prepared from Echinacea purpurea and Echinacea angustifolia on the response to Influenza A/PR/8/34 infection in mice. [D] . Singh, Navrozedeep. 2010

机译：从紫锥菊和紫锥菊中提取的水和乙醇提取物对小鼠对A / PR / 8/34流感的反应的比较。
6. Echinacea purpurea aerial extract alters course of influenza infection in mice [O] . Dahlene Fusco, Xinyan Liu, Caroline Savage, -1

机译：海胆亚紫癜鸟类提取物改变小鼠流感感染的课程
7. A comparison of both water and ethanol extracts prepared from Echinacea purpurea and Echinacea angustifolia on the response to Influenza A/PR/8/34 infection in mice [O] . Singh, Navrozedeep 2010

机译：紫锥菊和紫锥菊提取物的水和乙醇提取物对小鼠对A / PR / 8/34流感病毒感染反应的比较

Echinacea purpurea aerial extract alters course of influenza infection in mice

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