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Impact of mass vaccination with polysaccharide conjugate vaccine against serogroup C meningococcal disease in Spain

机译:多糖结合疫苗大规模接种疫苗对西班牙C群血清脑膜炎球菌疾病的影响

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摘要

During the fourth quarter of 1997, a vaccination campaign using the meningococcal C polysaccharide vaccine was carried out in 14 autonomous regions of Spain. The remaining three regions did not participate. In the last quarter of the year 2000, a mass vaccination campaign using the meningococcal C conjugated vaccine was carried out in all regions. In the year 2001 the incidence decreased in all regions, although the decrease was greater in regions that did not vaccinate in 1997. In contrast, case fatality rates did not decrease. During 200 1, the incidence rate of meningococcal C disease was still lower (0.32 per 100,000 persons-year) in the regions that vaccinated in 1997 with the polysaccharide vaccine than in those that did not (0.64 per 100,000 persons-year).
机译:1997年第四季度,在西班牙的14个自治区进行了使用脑膜炎球菌C多糖疫苗的疫苗接种运动。其余三个地区没有参加。在2000年最后一个季度,在所有地区都开展了使用脑膜炎球菌C结合疫苗的大规模疫苗接种运动。在2001年,所有地区的发病率均下降,尽管1997年未接种疫苗的地区的下降率更大。相比之下,病死率并未下降。在200年1月期间,1997年接种多糖疫苗的地区的脑膜炎球菌C病的发病率仍然较低(每10万人年0.32),而不是未接种多糖疫苗的地区(每10万人年0.64)。

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