Differences in the immune response to hepatitis B and Haemophilus influenzae type b vaccines in Guatemalan infants by ethnic group and nutritional status

Asturias EJ; Mayorga C; Caffaro C; Ramirez P; Ram M; Verstraeten T; Clemens R; Halsey NA

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Differences in the immune response to hepatitis B and Haemophilus influenzae type b vaccines in Guatemalan infants by ethnic group and nutritional status

机译：种族和营养状况对危地马拉婴儿对乙型肝炎和乙型流感嗜血杆菌疫苗的免疫应答差异

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Ladino and native Indian Guatemalan infants developed high rates (96-100%) of protective antibodies after receiving conjugate Haemophilus influenzae type b and hepatitis B vaccines at 2, 4 and 6 months of age. Native Indian infants developed significantly (p<0.01) higher geometric mean anti-PRP (polyribose-ribitol-phosphate) and anti-HBs (anti-hepatitis b surface) antibody concentrations than Ladino infants. Malnourished infants generally responded as well as healthy infants. Unvaccinated native Indian infants had higher rates of developing anti-PRP antibodies than Ladino infants by seven months of age.

机译：Ladino和印度裔危地马拉土著婴儿分别在2、4和6个月大时接受乙型流感嗜血杆菌和乙型肝炎疫苗后，产生了高比例的保护性抗体（96-100％）。与Ladino婴儿相比，印度土著婴儿的几何平均抗PRP（多核糖核糖磷酸）和抗HBs（抗乙型肝炎表面）抗体的几何平均浓度显着提高（p <0.01）。营养不良的婴儿通常对健康的婴儿也有反应。到七个月大时，未接种疫苗的印度土著婴儿的抗PRP抗体发生率要高于拉丁裔婴儿。

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来源
《Vaccine》 |2009年第27期|共5页
作者
Asturias EJ; Mayorga C; Caffaro C; Ramirez P; Ram M; Verstraeten T; Clemens R; Halsey NA;
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正文语种 eng
中图分类预防医学、卫生学;
关键词
bacterial diseases; conjugate vaccines; ethnic groups; hepatitis B; human diseases; immune response; immunization; infants; malnutrition; vaccination; Haemophilus influenzae type b; Hepatitis B virus; Guatemala;

机译：细菌性疾病;结合疫苗;族群;乙型肝炎;人类疾病;免疫反应;免疫;婴儿;营养不良;疫苗接种;b型流感嗜血杆菌;乙型肝炎病毒;危地马拉;

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专利

1. Differences in the immune response to hepatitis B and Haemophilus influenzae type b vaccines in Guatemalan infants by ethnic group and nutritional status [J] . Asturias EJ, Mayorga C, Caffaro C, Vaccine . 2009,第27期

机译：种族和营养状况对危地马拉婴儿对乙型肝炎和乙型流感嗜血杆菌疫苗的免疫应答差异
2. Hepatitis B Response of Premature Infants after Primary and Booster Immunisation with a Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Poliovir us/Haemophilus Influenzae Type B Vaccine [J] . Felix Omenaca, Jose Garcia Sicilia, Reyes Boceta, Infectious diseases in obstetrics and gynecology . 2010,第Infadiseaaandapremaa期

机译：白喉-破伤风-无细胞百日咳-乙型肝炎灭活的脊髓灰质炎病毒/流感嗜血杆菌B型疫苗的初次免疫和加强免疫后，早产儿的乙肝反应
3. Co-administration of a novel Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine does not interfere with the immune response to antigens contained in infant vaccines routinely used in the United States. [J] . Gary S Marshall, Colin D Marchant, Mark Blatter, Human vaccines . 2011,第2期

机译：新型b型流感嗜血杆菌和脑膜炎奈瑟氏球菌血清群C和Y-破伤风类毒素结合疫苗的共同给药不会干扰对美国常规使用的婴儿疫苗中所含抗原的免疫反应。
4. Wastage of Diphtheria, Tetanus, Pertussis and Haemophilus influenzae type-b vaccine (Tetravalent vaccine) and its impact on the increase of dose costs [C] . Novaes M. L. O., Almeida R. M. V., Bastos R. R., Pan American Health Care Exchanges Conference . 2011

机译：白喉，破伤风，百日咳和流感嗜血杆菌b型疫苗（四价疫苗）的浪费及其对剂量费用增加的影响
5. Protein Vaccines Against Acute Otitis Media Caused by Nontypeable Haemophilus influenzae in a Murine Model [D] . Zavorin, Mark. 2018

机译：蛋白质疫苗针对鼠模型中的不可迁移血液血液嗜血杆菌引起的急性中耳炎
6. Hepatitis B Response of Premature Infants after Primary and Booster Immunisation with a Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Poliovirus/Haemophilus Influenzae Type B Vaccine [O] . Felix Omeñaca, Jose Garcia-Sicilia, Reyes Boceta, 2010

机译：白喉-破伤风-无细胞百日咳-乙型肝炎灭活的脊髓灰质炎病毒/流感嗜血杆菌B型疫苗的初次免疫和加强免疫后早产儿的乙肝反应
7. Hepatitis B Response of Premature Infants after Primary and Booster Immunisation with a Diphtheria-Tetanus-Acellular Pertussis-Hepatitis B-Inactivated Poliovirus/Haemophilus Influenzae Type B Vaccine [O] . Omeñaca, Felix, Garcia-Sicilia, Jose, Boceta, Reyes, 2010

机译：白喉-破伤风-无细胞百日咳-乙型肝炎灭活的脊髓灰质炎病毒/流感嗜血杆菌B型疫苗的初次免疫和加强免疫后，早产儿的乙肝反应
8. Field Trial of Meningococcus Group A and 'Haemophilus influenzae' Type B Vaccines in Infants and Children 3 Months to 5 Years of Age: Long Term Sustenance of Immunity After Various Immunization Schedules [R] . Maekelae, P. H. , Peltola, H. , Kaeyhty, H. 1980

机译：婴儿和儿童3个月至5岁的脑膜炎球菌a组和'B型流感嗜血杆菌'疫苗的实地试验：各种免疫接种后的长期免疫保持

Differences in the immune response to hepatitis B and Haemophilus influenzae type b vaccines in Guatemalan infants by ethnic group and nutritional status

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