Studying experimental measles virus vaccines in the presence of maternal antibodies in the cotton rat model (Sigmodon hispidus)

Niewiesk S

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Studying experimental measles virus vaccines in the presence of maternal antibodies in the cotton rat model (Sigmodon hispidus)

机译：在棉鼠模型（Sigmodon hispidus）中，在母源抗体存在的情况下研究麻疹病毒疫苗实验

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The inhibition of vaccine-induced seroconversion after vaccination is one of the problems associated with measles virus (MV) immunization. In cotton rats, after transfer of human MV specific antibodies, vaccine-induced seroconversion is inhibited. With this model, it was shown that plasmid immunization (although successful in seronegative animals) was inhibited by maternal antibodies. In contrast, immunization via a mucosal surface with a vesicular stomatitis virus expressing the MV hemagglutinin induced seroconversion in the presence of maternal antibodies and subsequent protection.

机译：疫苗接种后疫苗诱导的血清转化的抑制是与麻疹病毒（MV）免疫相关的问题之一。在棉鼠中，转移人MV特异性抗体后，疫苗诱导的血清转化被抑制。利用该模型，表明母源抗体抑制了质粒免疫（尽管在血清阴性动物中是成功的）。相反，在母体抗体的存在下，通过表达MV血凝素的水疱性口炎病毒经粘膜表面免疫诱导血清转化，并提供随后的保护。

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《Vaccine》 |2001年第19期|共4页
作者
Niewiesk S;
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正文语种 eng
中图分类卫生标准、卫生检查、医药管理;
关键词
Vesicular stomatitis viruses; Day-old piglets; Rubella immunization; Transgenic mice; Plasmid dna; Infection; Strains; Cd46; Vaccination; Replication;

机译：水泡性口腔炎病毒;日龄仔猪;Rubella免疫;转基因小鼠;质粒dna;感染;菌株;Cd46;疫苗接种;复制;

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1. Studying experimental measles virus vaccines in the presence of maternal antibodies in the cotton rat model (Sigmodon hispidus) [J] . Niewiesk S Vaccine . 2001,第17a19期

机译：在棉鼠模型（Sigmodon hispidus）中，在母源抗体存在的情况下研究麻疹病毒疫苗实验
2. Experimental Everglades Virus Infection of Cotton Rats (Sigmodon hispidus) [J] . L. L. Coffey, Anne-Sophie Carrara, Slobodan Paessler, Emerging Infectious Diseases . 2004,第12期

机译：实验性大沼泽地病毒感染棉鼠（Sigmodon hispidus）
3. Efficacy of trivalent inactivated influenza vaccines in the cotton rat Sigmodon hispidus model. [J] . Yim K., Miles B., Zinsou R., Vaccine . 2012,第7期

机译：三价灭活流感疫苗在棉鼠 Sigmodon hispidus 模型中的功效。
4. Evaluation of antibody titer of the weaned pig following vaccination with a killed influenza A virus vaccine in the presence of maternal antibodies both pre and post heterologous influenza A virus cha [C] . Annual Meeting of the American Association of Swine Veterinarians . 2018

机译：在母体抗体存在下用杀死的流感疫苗疫苗接种后断奶猪的抗体滴度评价母体抗体的疫苗术前和后异源甲型血清血清血清
5. A measles DNA vaccine administered at birth in the presence of passive antibodies protects against measles [D] . Premenko-Lanier, Mary F. 2003

机译：出生时在存在被动抗体的情况下接种的麻疹DNA疫苗可预防麻疹
6. Extent of Measles Virus Spread and Immune Suppression Differentiates between Wild-Type and Vaccine Strains in the Cotton Rat Model (Sigmodon hispidus) [O] . Joanna Pfeuffer, Karen Püschel, Volker ter Meulen, 2003

机译：棉鼠模型（Sigmodon hispidus）的麻疹病毒传播程度和免疫抑制程度在野生型和疫苗株之间有所区别。
7. Extent of Measles Virus Spread and Immune Suppression Differentiates between Wild-Type and Vaccine Strains in the Cotton Rat Model (Sigmodon hispidus) [O] . Pfeuffer, Joanna, Püschel, Karen, Meulen, Volker ter, 2003

机译：棉鼠模型（Sigmodon hispidus）中麻疹病毒传播的程度和免疫抑制在野生型和疫苗株之间的区别。
8. Isoagglutination and Heteroagglutination of the Erythrocytes of the Cotton Rat, Sigmodon Hispidus Texianus, and the Reactions of Cotton Rat Plasmas with Human Erythrocytes. [R] . Leone, C. A., Dolyak, F., Truffelli, G. T. 1952

机译：棉花鼠sigtron Hispidus Texianus红细胞的异凝集和杂交，以及棉鼠血浆与人红细胞的反应。

Studying experimental measles virus vaccines in the presence of maternal antibodies in the cotton rat model (Sigmodon hispidus)

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