Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers

Olander RM; Wuorimaa T; Kayhty H; Leroy O; Dagan R; Eskola J

首页> 外文期刊>Vaccine >Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers

【24h】

Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers

机译：成人和幼儿对11价肺炎球菌结合疫苗的破伤风和白喉类毒素载体的增强反应

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We measured the tetanus and diphtheria antitoxin responses after administration of one dose of a mixed carrier (tetanus and diphtheria toxoids) 11-valent pneumococcal conjugate vaccine (PncDT) in 20 Finnish adults (mean age 26.1 years) and 20 Finnish (mean age 23.2 months) and 23 Israeli (mean age 18.5 months) toddlers. The vaccinees had previously been immunised with multiple doses of vaccines containing diphtheria and tetanus toxoids. A double-antigen ELISA was used to measure the antitoxin concentrations. PncDT induced significant booster responses in both adults and toddlers to the tetanus and the diphtheria carrier proteins. Thus, the effect on the tetanus and diphtheria immunity of multivalent conjugate vaccines containing tetanus and diphtheria toxoids as carriers needs to be evaluated before such vaccines are routinely implemented.

机译：我们在20名芬兰成年人（平均年龄26.1岁）和20名芬兰成年人（平均年龄23.2个月）中服用一剂混合载体（破伤风和白喉类毒素）11价肺炎球菌结合疫苗（PncDT）后，测量了破伤风和白喉的抗毒素反应）和23名以色列（平均年龄18.5个月）幼儿。以前已经用多剂量的含有白喉和破伤风类毒素的疫苗免疫了疫苗。双重抗原ELISA用于测量抗毒素浓度。 PncDT在成人和幼儿中均对破伤风和白喉载体蛋白产生明显的增强反应。因此，在常规接种破伤风和白喉类毒素作为载体的多价结合疫苗中，需要评估其对破伤风和白喉免疫力的影响。

著录项

来源
《Vaccine》 |2001年第4期|共6页
作者
Olander RM; Wuorimaa T; Kayhty H; Leroy O; Dagan R; Eskola J;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类卫生标准、卫生检查、医药管理;
关键词
Diphtheria; Tetanus; Immunity; Conjugate vaccines; Influenzae type-b; Antibody-response; Serum antibodies; Polysaccharide; Injection; Infants;

机译：白喉;破伤风;免疫;结合疫苗;b型流感;抗体反应;血清抗体;多糖;注射剂;婴儿;

相似文献

外文文献
中文文献
专利

1. Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers [J] . Olander RM, Wuorimaa T, Kayhty H, Vaccine . 2001,第3a4期

机译：成人和幼儿对11价肺炎球菌结合疫苗的破伤风和白喉类毒素载体的增强反应
2. Functional antibodies elicited by an 11-valent diphtheria-tetanus toxoid-conjugated pneumococcal vaccine. [J] . Puumalainen T, Ekstrom N, Zeta Capeding R, The Journal of Infectious Diseases . 2003,第11期

机译：由11价白喉-破伤风类毒素结合的肺炎球菌疫苗引发的功能性抗体。
3. Immunogenicity and safety of a booster dose of the 10-valent pneumococcal haemophilus influenzae protein D conjugate vaccine coadministered with the tetravalent meningococcal serogroups A, C, W-135 and y tetanus toxoid conjugate vaccine in toddlers: A randomized trial [J] . The Pediatric infectious disease journal . 2013,第1期

机译：加强剂量的10价肺炎球菌流感嗜血杆菌流感病毒D蛋白结合疫苗与四价脑膜炎球菌血清群A，C，W-135和破伤风类毒素结合疫苗的幼儿：一项随机试验
4. Wastage of Diphtheria, Tetanus, Pertussis and Haemophilus influenzae type-b vaccine (Tetravalent vaccine) and its impact on the increase of dose costs [C] . Novaes M. L. O., Almeida R. M. V., Bastos R. R., Pan American Health Care Exchanges Conference . 2011

机译：白喉，破伤风，百日咳和流感嗜血杆菌b型疫苗（四价疫苗）的浪费及其对剂量费用增加的影响
5. Immune responses of pneumococcal polysaccharide and conjugate vaccines in adults: Effect of human immunodeficiency virus infection [D] . Ahmed, Faruque 1995

机译：成人肺炎球菌多糖和结合疫苗的免疫应答：人类免疫缺陷病毒感染的影响
6. An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid tetanus toxoid 3-component acellular pertussis hepatitis B inactivated poliovirus and Haemophilus influenzae type b vaccine [O] . Markus A Rose, Christine Juergens, Beate Schmoele-Thoma, 2013

机译：预防性扑热息痛与7价肺炎球菌结合疫苗六价白喉类毒素破伤风类毒素3组分无细胞百日咳乙型肝炎灭活的脊髓灰质炎病毒和乙型流感嗜血杆菌疫苗并用的开放标签随机临床试验
7. Administration of Combined Diphtheria and Tetanus Toxoids and Pertussis Vaccine, Hepatitis B Vaccine, andHaemophilus influenzaeType b (Hib) Vaccine to Infants and Response to a Booster Dose of Hib Conjugate Vaccine [O] . Michael E. Pichichero, Sherry Passador 1997

机译：婴儿的婴儿疫苗，乙型肝炎毒素，乙型肝炎疫苗，乙型肝炎疫苗，丙型肝炎疫苗，乙型肝炎疫苗，对婴儿的疫苗和反应患者
8. Preventing Tetanus, Diphtheria, and Pertussis Among Adults: Use of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine: Recommendation of ACIP, Supported by the Healthcare Infection Control Practices Advisory Committee (HICPAC), [R] . Kretsinger, K. 2006

机译：在成人中预防破伤风，白喉和百日咳：使用破伤风类毒素，减少白喉类毒素和无细胞百日咳疫苗：aCIp的推荐，由医疗保健感染控制实践咨询委员会（HICpaC）支持，

Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers

摘要

著录项

相似文献

相关主题

期刊订阅