Using oral polio vaccine beyond the cold chain: a feasibility study conducted during the national immunization campaign in Mali.

Halm A.; Yalcouye I.; Kamissoko M.; Keita T.; Modjirom N.; Zipursky S.; Kartoglu U.; Ronveaux O.

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Using oral polio vaccine beyond the cold chain: a feasibility study conducted during the national immunization campaign in Mali.

机译：在冷链之外使用口服脊髓灰质炎疫苗：在马里举行的全国免疫运动中进行的可行性研究。

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We conducted the first systematic documentation of using oral polio vaccine (OPV) out of the cold chain during national immunization day (NID) campaigns in Mali. Using a crossover intervention design, vaccinators compared the transport of OPV in vaccine carriers with or without ice packs. Vaccine integrity was assured through monitoring vaccine vial monitor (VVM) status. Despite ambient temperatures up to 40 degrees C, none of the VVMs on any of the vials used (n=956) reached their discard point. Over 90% of vaccinators and supervisors preferred conducting NIDs without ice packs. In addition, using OPV out of the cold chain reduced vaccine wastage resulting from melting ice packs causing labels to detach from the vial.

机译：我们在马里举行的全国免疫日（NID）活动期间进行了冷链外使用口服脊髓灰质炎疫苗（OPV）的第一份系统性文件。疫苗接种者使用交叉干预设计，比较了有或没有冰袋的疫苗载体中OPV的运输。通过监测疫苗瓶监测器（VVM）的状态来确保疫苗的完整性。尽管环境温度高达40摄氏度，但使用的任何样品瓶（ n = 956）上的VVM均未达到丢弃点。超过90％的疫苗接种者和监督者更喜欢在没有冰袋的情况下进行NID。此外，在冷链中使用OPV可以减少因冰袋融化导致标签从小瓶分离而造成的疫苗浪费。

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来源
《Vaccine》 |2010年第19期|共6页
作者
Halm A.; Yalcouye I.; Kamissoko M.; Keita T.; Modjirom N.; Zipursky S.; Kartoglu U.; Ronveaux O.;
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正文语种 eng
中图分类医学免疫学;
关键词
carriers; environmental temperature; feasibility studies; immunization programmes; poliomyelitis; quality; refrigerated transport; temperature; vaccines; Poliovirus; Mali;

机译：携带者;环境温度;可行性研究;免疫程序;脊髓灰质炎;质量;冷藏运输;温度;疫苗;脊髓灰质炎病毒;马里;

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1. Using oral polio vaccine beyond the cold chain: a feasibility study conducted during the national immunization campaign in Mali. [J] . Halm A., Yalcouye I., Kamissoko M., Vaccine . 2010,第19期

机译：在冷链之外使用口服脊髓灰质炎疫苗：在马里举行的全国免疫运动中进行的可行性研究。
2. Assessing the potency of oral polio vaccine kept outside of the cold chain during a national immunization campaign in Chad [J] . Zipursky Simona, Boualam Liliane, Cheikh Dah Ould, Vaccine . 2011,第34期

机译：在乍得的全国免疫运动中评估冷链外保存的口服脊髓灰质炎疫苗的效力
3. National Immunization Campaigns with Oral Polio Vaccine Reduce All-Cause Mortality: A Natural Experiment within Seven Randomized Trials [J] . Andreas Andersen, Ane Baerent Fisker, Amabelia Rodrigues, Frontiers in Public Health . 2018,第1期

机译：口服脊髓灰质炎疫苗的全国免疫运动降低全因死亡率：七个随机试验中的一项自然实验
4. Supporting immunization programs with improved vaccine cold chain information systems [C] . Anderson R., Perrier T., Pervaiz F., IEEE Global Humanitarian Technology Conference . 2014

机译：通过改进的疫苗冷链信息系统支持免疫计划
5. Immunogenicity of quadrivalent meningococcal polysaccharide vaccine in children during a mass immunization campaign [D] . King, W. James 1995

机译：儿童大规模免疫接种过程中四价脑膜炎球菌多糖疫苗的免疫原性
6. National Immunization Campaigns with Oral Polio Vaccine Reduce All-Cause Mortality: A Natural Experiment within Seven Randomized Trials [O] . Andreas Andersen, Ane Baerent Fisker, Amabelia Rodrigues, 2018

机译：口服脊髓灰质炎疫苗的全国免疫运动降低全因死亡率：七个随机试验中的一项自然实验
7. Introduction of Sequential Inactivated Polio Vaccine-Oral Polio Vaccine Schedule for Routine Infant Immunization in Brazil's National Immunization Program [O] . C. M. A. S. Domingues, S. de Fatima Pereira, A. C. Cunha Marreiros, 2014

机译：在巴西国家免疫计划中引入序贯灭活脊髓灰质炎疫苗 - 口服脊髓灰质炎疫苗疫苗时间表

Using oral polio vaccine beyond the cold chain: a feasibility study conducted during the national immunization campaign in Mali.

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