Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds

Smith Kenneth J.; Lee Bruce Y.; Nowalk Mary Patricia; Raymund Mahlon; Zimmerman Richard K. .

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Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds

机译：50岁儿童双重流感和肺炎球菌双重疫苗接种的成本效益

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Influenza vaccination is now recommended for all ages; CDC pneumococcal polysaccharide vaccination (PPV) recommendations are comorbidity-based in nonelderly patients. We constructed a Markov model to estimate the cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds. Patients were followed for 10 years, with differing time horizons examined in sensitivity analyses. With 100% vaccine uptake, dual vaccination cost $37,700/QALY gained compared to a CDC recommendation strategy; with observed vaccine uptake, dual vaccination cost $5,300/QALY. Results were sensitive to shorter time horizons, favoring CDC recommendations. We found dual vaccination of all 50-year-olds economically reasonable. Shorter duration models may not fully account for PPV effectiveness

机译：现在建议所有年龄段的人都接种流感疫苗; CDC肺炎球菌多糖疫苗（PPV）建议在非老年患者中以合并症为基础。我们构建了一个马尔可夫模型，以评估50岁以下人群双重流感和肺炎球菌双重疫苗接种的成本效益。随访患者10年，在敏感性分析中检查了不同的时间范围。与CDC推荐策略相比，采用100％的疫苗摄入量，双重疫苗接种每QALY的费用为$ 37,700;观察到的疫苗摄取情况，双重疫苗接种费用为$ 5,300 / QALY。结果对较短的时间范围很敏感，因此倾向于CDC的建议。我们发现在经济上对所有50岁的孩子进行双重疫苗接种是合理的。持续时间较短的模型可能无法完全说明PPV的有效性

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《Vaccine》 |2010年第48期|共6页
作者
Smith Kenneth J.; Lee Bruce Y.; Nowalk Mary Patricia; Raymund Mahlon; Zimmerman Richard K. .;
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正文语种 eng
中图分类医学免疫学;
关键词
pneumococcal polysaccharide vaccine: immunologic-drug; immunostimulant-drug; vaccine; influenza vaccine: immunologic-drug; immunostimulant-drug; vaccine; dual vaccine cost-effectiveness;

机译：肺炎球菌多糖疫苗：免疫药物;免疫刺激药物;疫苗;流感疫苗：免疫药物;免疫刺激药物;疫苗;双重疫苗成本效益;

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1. Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds [J] . Smith Kenneth J., Lee Bruce Y., Nowalk Mary Patricia, Vaccine . 2010,第48期

机译：50岁儿童双重流感和肺炎球菌双重疫苗接种的成本效益
2. Effectiveness and safety of dual influenza and pneumococcal vaccination versus separate administration or no vaccination in older adults: a meta-analysis [J] . Mingjuan Yin, Lingfeng Huang, Yan Zhang, Expert review of vaccines . 2018,第7a12期

机译：双流感和肺炎球菌疫苗接种的有效性和安全性与老年人的单独给药或没有疫苗接种：荟萃分析
3. Prevention of mortality and pneumonia among nursing home older adults by dual pneumococcal and seasonal influenza vaccination during a pandemic caused by novel pandemic influenza A (H1N1). [J] . Tuen-Ching Chan, Ivan Fan-Ngai Hung, James Ka-Hay Luk, Journal of the American Medical Directors Association . 2012,第8期

机译：在新型甲型大流行性流感（H1N1）引起的大流行期间，通过双重肺炎球菌和季节性流感疫苗接种预防养老院老年人的死亡率和肺炎。
4. MULTI-TASKING AN INACTIVATED INFLUENZA VACCINE TO PROVIDE RAPID INNATE IMMUNE SYSTEM-MEDIATED AND SUBSEQUENT LONG-TERM ADAPTIVE IMMUNITY AGAINST INFLUENZA AND SECONDARY PNEUMOCOCCAL INFECTIONS [C] . Brendon Y Chua, Chinn Yi Wong, Edin J Mifsud, Vaccine technology VI . 2016

机译：多次服用灭活的流感疫苗，以提供快速的天然免疫系统介导的和随后的长期适应性免疫力，以应对流感和第二次肺炎球菌感染
5. Perceived Barriers to Routine Adult Influenza and Pneumococcal Vaccination in the Emergency Department. [D] . Amberge, Westin M. 2011

机译：急诊科对常规成人流感和肺炎球菌疫苗的认知障碍。
6. Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds [O] . Kenneth J Smith, Bruce Y. Lee, Mary Patricia Nowalk, -1

机译：50岁儿童双流感和肺炎球菌疫苗接种的成本效益
7. Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds [O] . Kenneth J. Smith, Bruce Y. Lee, Mary Patricia Nowalk, 2010

机译：50岁儿童双流感和肺炎球菌疫苗接种的成本效益

Cost-effectiveness of dual influenza and pneumococcal vaccination in 50-year-olds

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