Enhancement of DNA vaccine potency in rhesus macaques by electroporation

Otten G; Schaefer M; Doe B; Liu H; Srivastava I; zur Megede J

首页> 外文期刊>Vaccine >Enhancement of DNA vaccine potency in rhesus macaques by electroporation

【24h】

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

机译：通过电穿孔增强恒河猴的DNA疫苗效力

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The potency of an HIV DNA vaccine was enhanced in rhesus macaques by in vivo electroporation, as judged by increased onset, magnitude and duration of antibody and cell-mediated immune responses against both components of a combination Gag and Env vaccine. These data demonstrate the utility of the electroporation technology for use in large animals.

机译：通过体内电穿孔增强了恒河猴猕猴中HIV DNA疫苗的效力，这可以通过抗体的发作，幅度和持续时间的增加以及针对组合Gag和Env疫苗的两种成分的细胞介导的免疫反应来判断。这些数据证明了电穿孔技术用于大型动物的效用。

著录项

来源
《Vaccine》 |2004年第19期|共5页
作者
Otten G; Schaefer M; Doe B; Liu H; Srivastava I; zur Megede J;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类卫生标准、卫生检查、医药管理;
关键词
Dna; Electroporation; Vaccine; Hiv; Human-immunodeficiency-virus; Cytotoxic t-lymphocytes; Immune-responses; In-vivo; Intramuscular injection; Envelope glycoprotein; Malaria; vaccine; Gene-transfer; Large animals; Induction;

机译：Dna;电气化;疫苗;HIV;人类免疫缺陷病毒;细胞毒性T淋巴细胞;免疫反应;体内;肌肉注射;包膜糖蛋白;疟疾;疫苗;基因转移;大型动物;诱导;

相似文献

外文文献
中文文献
专利

1. Enhancement of DNA vaccine potency in rhesus macaques by electroporation [J] . Otten G, Schaefer M, Doe B, Vaccine . 2004,第19期

机译：通过电穿孔增强恒河猴的DNA疫苗效力
2. Comparative functional potency of DNA vaccines encoding ce:italic>Plasmodium falciparum/ce:italic> transmission blocking target antigens Pfs48/45 and Pfs25 administered alone or in combination by ce:italic>in vivo/ce:italic> electroporation in rhesus macaques [J] . Dibyadyuti Datta, Geetha P. Bansal, Brooke Grasperge, Vaccine . 2017,第50期

机译：DNA疫苗编码的比较功能效力。斜体>疟原虫纤维膏＆ / ce：斜体>透射率诱导靶抗原PFS48 / 45和PFS25单独给药或组合施用的＆LT; / CE：Italic> Italic> 恒河猕猴的电穿孔
3. Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques [J] . Hirao LA, Wu L, Khan AS, Vaccine . 2008,第3期

机译：通过电穿孔进行皮内/皮下免疫可提高质粒疫苗在猪和恒河猴中的递送效率
4. ENHANCED IMMUNE RESPONSES INDUCED IN RHESUS MACAQUES BY PLASMID DNA DELIVERED ON CATIONIC MICROPARTICLES [C] . M. Ugozzoli, M. Singh, J. Kazzaz, International symposium on controlled release of bioactive materials;Consumer diversified products conference . 2001

机译：阳离子微粒释放的类固醇DNA增强了猕猴的免疫反应
5. Characterization of viral envelopes and cytokine responses among rhesus macaques immunized with vesicular stomatitis virus-based simian immunodeficiency virus (SIV) vaccines and challenged with pathogenic SIV. [D] . Gambhira, Ratish. 2012

机译：基于水泡性口炎病毒的猿猴免疫缺陷病毒（SIV）疫苗免疫并受到病原性SIV攻击的恒河猴的病毒包膜和细胞因子应答的特征。
6. Comparative functional potency of DNA vaccines encoding Plasmodium falciparum transmission blocking target antigens Pfs48/45 and Pfs25 administered alone or in combination by in vivo electroporation in rhesus macaques [O] . Dibyadyuti Datta, Geetha P. Bansal, Brooke Grasperge, -1

机译：编码恶性疟原虫传播阻断靶抗原Pfs48 / 45和Pfs25的DNA疫苗在猕猴中单独或联合体内电穿孔给药的比较功能效能
7. Comparative functional potency of DNA vaccines encoding Plasmodium falciparum transmission blocking target antigens Pfs48/45 and Pfs25 administered alone or in combination by in vivo electroporation in rhesus macaques [O] . Dibyadyuti Datta, Geetha P. Bansal, Brooke Grasperge, 2017

机译：DNA疫苗的比较功能效力编码疟原虫透射率阻断靶抗原PFS48 / 45和PFS25单独给药或组合在恒河猴中的电穿孔组合

相关主题

Enhancement of DNA vaccine potency in rhesus macaques by electroporation

摘要

著录项

相似文献

相关主题

期刊订阅