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首页> 外文期刊>Dermatologic surgery >The use of high-frequency ultrasound in the evaluation of superficial and nodular basal cell carcinomas.
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The use of high-frequency ultrasound in the evaluation of superficial and nodular basal cell carcinomas.

机译：高频超声在浅表和结节性基底细胞癌评估中的应用。

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BACKGROUND: Frequencies of 20 MHz may be appropriate to visualize basal cell carcinomas (BCCs) including their tumor thickness and margins. Histologic comparisons to sonographic images are related at all levels of the epidermis and corium. OBJECTIVE: The objective was to evaluate whether high-frequency ultrasound (HFUS) proved to be an inexpensive and noninvasive modality to adequately delineate tumor margins under favorable circumstances. MATERIALS AND METHODS: Fifty superficial and nodular BCCs of various locations were scanned using a 20-MHz ultrasound device. Tumors were delineated, excised with 4-mm surgical margins, and sent for histologic clearance. Morpheaform, recurrent BCCs, BCCs in areas difficult to scan, and BCCs with specific properties were excluded from this study. RESULTS Clinical and ultrasonic measurements correlated well in terms of width, depth, and length (p<.0005). Of 50 BCCs, 45 were clear after margin assessment with HFUS. Five BCCs depicted extension past 4-mm surgical marginsand returned with positive margins. CONCLUSION: HFUS delineated tumor margins adequately, and it appeared to depict subclinical extension past 4 mm on less aggressive BCC variants. It could be warranted if clinical or histologic diagnosis is uncertain. The strong association between clinical and ultrasonic measurements initiates more successful forms of therapy, risk-stratifies specific subgroups of patients, and prevents overall morbidity.
机译：背景：20 MHz的频率可能适合可视化基底细胞癌（BCC），包括其肿瘤的厚度和边界。与超声图像的组织学比较在表皮和皮质的所有水平上都相关。目的：目的是评估高频超声（HFUS）是否被证明是一种廉价且无创的方法，可以在有利的情况下充分描绘出肿瘤的边缘。材料与方法：使用20 MHz超声设备扫描了50个不同位置的浅表和结节性BCC。划定肿瘤，用4mm手术切缘切除，并送去组织学清除。本研究不包括睡眠形态，复发性BCC，难以扫描的BCC和具有特定性质的BCC。结果临床和超声测量在宽度，深度和长度方面具有很好的相关性（p <.0005）。在使用HFUS进行边际评估后，在50个BCC中，有45个清晰可见。五个BCC描绘了超过4毫米手术切缘的延伸，并以正切缘返回。结论：HFUS充分描绘了肿瘤边缘，并且似乎描绘了在侵略性较低的BCC变体上亚临床扩展超过4 mm。如果临床或组织学诊断不确定，则可以保证。临床和超声测量结果之间的密切联系启动了更成功的治疗形式，对患者的特定亚组进行了风险分层，并防止了整体发病率。

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