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Drug fever as an adverse effect of acitretin in complicated psoriasis patient

机译:药物热是阿维A在复杂牛皮癣患者中的不良反应

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摘要

We present a case of a 63-year old man with severe chronic plaque psoriasis and a recent history of lung cancer, wherein fever appeared suddenly after initiation of treatment with low dose acitretin. Tumor recurrence or infection was not found during extensive examinations, nevertheless the patient was empirically treated with broad-spectrum antibiotics without any effect on fever. Immediately after discontinuation of acitretin therapy, the fever disappeared. The patient was followed for next 2 years, during this period similar problems did not reappear, although there has been a relapse of psoriasis and the patient was switched later on biological treatment.
机译:我们介绍了一例63岁的男子,患有严重的慢性斑块状牛皮癣和近期的肺癌病史,其中开始用小剂量阿维A肽治疗后突然发烧。在广泛的检查中未发现肿瘤复发或感染,但是根据经验对患者进行了广谱抗生素治疗,但对发烧没有任何影响。阿维A酸治疗终止后,发烧立即消失。对该患者进行了为期2年的随访,尽管牛皮癣已复发,但在此期间没有再出现类似的问题,并且该患者后来接受了生物治疗。

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