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首页> 外文期刊>Dermatitis: contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group >Contact Allergy to Surfactants in a Hypoallergenic Liquid Cleanser
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Contact Allergy to Surfactants in a Hypoallergenic Liquid Cleanser

机译：在低过敏性液体清洁剂中接触对表面活性剂的过敏

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摘要

Surfactants are a relatively rare cause of allergic contact dermatitis (ACD) and testing patients to personal care products containing these ingredients has historically been difficult given their irritant properties. Using the semiopen technique, we were able to identify ACD to a hypoallergenic liquid cleanser in 2 patients who presented to our patch test clinic only months apart. Additional patch testing to individual ingredients led to subsequent identification of 3 novel surfactant allergens (sodium lauroyl sarcosinate, isostearamidopropyl morpholine lactate, and disodium lauroamphodiacetate). Only one of these allergens, sodium lauroyl sarcosinate, has previously been reported as a cause of ACD.
机译：表面活性剂是过敏性接触性皮炎（ACD）的一种相对罕见的病因，鉴于其刺激性，从历史上讲很难对患者进行含有这些成分的个人护理产品的测试。使用半开放式技术，我们能够在仅隔月就诊给我们斑贴测试诊所的2名患者中鉴定出低过敏性液体清洁剂中的ACD。对各个成分进行的附加贴剂测试导致随后鉴定了3种新的表面活性剂过敏原（月桂酰肌氨酸钠，异硬脂酰胺基丙基吗啉乳酸和月桂酰两乙酸二钠）。这些变应原中只有一种是月桂酰肌氨酸钠，据报道是ACD的病因。

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