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The rising prevalence of diabetes and impaired glucose tolerance: the Australian Diabetes, Obesity and Lifestyle Study.

机译:糖尿病患病率上升和葡萄糖耐量降低:澳大利亚糖尿病,肥胖和生活方式研究。

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OBJECTIVE: To determine the population-based prevalence of diabetes and other categories of glucose intolerance (impaired glucose tolerance [IGT] and impaired fasting glucose [IFG]) in Australia and to compare the prevalence with previous Australian data. RESEARCH DESIGN AND METHODS: A national sample involving 11,247 participants aged > or =25 years living in 42 randomly selected areas from the six states and the Northern Territory were examined in a cross-sectional survey using the 75-g oral glucose tolerance test to assess fasting and 2-h plasma glucose concentrations. The World Health Organization diagnostic criteria were used to determine the prevalence of abnormal glucose tolerance. RESULTS: The prevalence of diabetes in Australia was 8.0% in men and 6.8% in women, and an additional 17.4% of men and 15.4% of women had IGT or IFG. Even in the youngest age group (25-34 years), 5.7% of subjects had abnormal glucose tolerance. The overall diabetes prevalence in Australia was 7.4%, and an additional 16.4% had IGT or IFG. Diabetes prevalence has more than doubled since 1981, and this is only partially explained by changes in age profile and obesity. CONCLUSIONS: Australia has a rapidly rising prevalence of diabetes and other categories of abnormal glucose tolerance. The prevalence of abnormal glucose tolerance in Australia is one of the highest yet reported from a developed nation with a predominantly Europid background.
机译:目的:确定澳大利亚人群的糖尿病患病率以及其他类别的葡萄糖耐量(糖耐量降低[IGT]和空腹血糖受损[IFG]),并将其与澳大利亚以前的数据进行比较。研究设计和方法:采用75克口服葡萄糖耐量试验,在横断面调查中对来自11个州的247名年龄≥25岁的参与者进行了抽样研究,这些参与者来自6个州和北领地的42个随机选择区域。空腹和2小时血浆葡萄糖浓度。世界卫生组织的诊断标准用于确定异常葡萄糖耐量的患病率。结果:澳大利亚的糖尿病患病率是男性为8.0%,女性为6.8%,另外有17.4%的男性和15.4%的女性患有IGT或IFG。即使在最年轻的年龄组(25-34岁)中,5.7%的受试者葡萄糖耐量异常。澳大利亚的总体糖尿病患病率为7.4%,另有16.4%的患者患有IGT或IFG。自1981年以来,糖尿病患病率增加了一倍以上,而这只能部分地由年龄特征和肥胖症的变化来解释。结论:澳大利亚的糖尿病和其他类别的葡萄糖耐量异常的患病率迅速上升。在澳大利亚,糖耐量异常的患病率是有欧洲血统背景的发达国家报告的最高水平之一。

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