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Higher-than-optimal body mass index and diabetes mortality in the Asia Pacific region

机译:亚太地区高于最佳的体重指数和糖尿病死亡率

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Aims: To estimate the population attributable fraction (PAF) of elevated body mass index (BMI) for diabetes mortality by country, sex and age group, for the Western Pacific and South-East Asia regions. Methods: Published data on nationally representative mean BMI (since year 2000) and age-specific hazard ratios for death due to diabetes for a unit increase in BMI were used to calculate PAFs using the methodology of the WHO Global Burden of Disease project, taking a BMI of 21kg/m 2 as the ideal. Results: Data were available for 15 countries in the Western Pacific and South East Asia regions. This included data from 330,374 individuals. Age-standardized male PAFs ranged from 11% for India to 98% for American Samoa. Age-standardized female PAFs ranged from 9% in India to 95% in American Samoa. For males, several countries had PAFs at or below 30% - these were India, Indonesia and Japan; whereas, India and Indonesia were the only two countries with PAFs below approximately 30% for females. Conclusion: Although this study is not a trial and thus not able to definitively state the proportions of diabetes deaths that could be averted by reducing mean BMI, this paper demonstrates that theoretically between 9% and 98% of deaths from diabetes could be prevented by tackling obesity in the Asia Pacific region. Preventing these deaths is likely to have an enormous positive social and economic impact, particularly in this region consisting of many low and middle-income countries.
机译:目的:按国家,性别和年龄组,估计西太平洋和东南亚地区因糖尿病而升高的体重指数(BMI)的人群归因分数(PAF)。方法:采用世界卫生组织全球疾病负担项目的方法,使用已发布的全国代表性平均BMI(自2000年起)数据和因BMI单位增加而导致的糖尿病死亡的特定年龄段危险比来计算PAF。理想的BMI为21kg / m 2。结果:可获得西太平洋和东南亚地区15个国家的数据。这包括来自330,374个人的数据。年龄标准化的男性PAF从印度的11%到萨摩亚的98%不等。年龄标准化的女性PA​​F从印度的9%到萨摩亚的95%不等。对于男性,有几个国家的PAF在30%或以下,分别是印度,印度尼西亚和日本。而印度和印度尼西亚是仅有的两个女性PAF低于30%的国家。结论:尽管该研究不是一项试验,因此无法确切说明可通过降低平均BMI避免的糖尿病死亡比例,但该论文表明,从理论上讲,通过解决该疾病,可以预防9%至98%的糖尿病死亡亚太地区的肥胖症。预防这些死亡可能会对社会和经济产生巨大的积极影响,特别是在这个由许多中低收入国家组成的地区。

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