BAP1 Immunostain and CDKN2A (p16) FISH Analysis Clinical Applicability for the Diagnosis of Malignant Mesothelioma in Effusions

Walts Ann E.; Hiroshima Kenzo; McGregor Stephanie M.; Wu Di; Husain Aliya N.; Marchevsky Alberto M.

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BAP1 Immunostain and CDKN2A (p16) FISH Analysis Clinical Applicability for the Diagnosis of Malignant Mesothelioma in Effusions

机译：BAP1免疫染色和CDKN2A（p16）FISH分析在输液中恶性间皮瘤诊断中的临床适用性

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Background: Loss of BAP1 by immunohistochemistry (IHC) and CDKN2A(p16) deletion by fluorescence in situ hybridization (FISH) have been proposed to distinguish malignant mesothelioma (MM) from atypical reactive mesothelial proliferations (ARMP) in effusions but it is uncertain whether both tests are needed routinely.

机译：背景：已提出通过免疫组织化学（IHC）丧失BAP1和通过荧光原位杂交（FISH）缺失CDKN2A（p16）来区分积液中的恶性间皮瘤（MM）与非典型反应性间皮增生（ARMP），但尚不确定通常需要进行测试。

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《Diagnostic cytopathology》 |2016年第7期|共8页
作者
Walts Ann E.; Hiroshima Kenzo; McGregor Stephanie M.; Wu Di; Husain Aliya N.; Marchevsky Alberto M.;
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正文语种 eng
中图分类病理学;
关键词
effusion; malignant mesothelioma; CDKN2A (p16) FISH; BAP1;

机译：积液;恶性间皮瘤;CDKN2A（p16）FISH;BAP1;

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1. BAP1 Immunostain and CDKN2A (p16) FISH Analysis Clinical Applicability for the Diagnosis of Malignant Mesothelioma in Effusions [J] . Walts Ann E., Hiroshima Kenzo, McGregor Stephanie M., Diagnostic cytopathology . 2016,第7期

机译：BAP1免疫染色和CDKN2A（p16）FISH分析在输液中恶性间皮瘤诊断中的临床适用性
2. BAP1 immunohistochemistry and p16 FISH results in combination provide higher confidence in malignant pleural mesothelioma diagnosis: ROC analysis of the two tests [J] . Hida Tomoyuki, Hamasaki Makoto, Matsumoto Shinji, Pathology International . 2016,第10期

机译：BAP1免疫组化和p16 FISH结果的结合可提高对恶性胸膜间皮瘤诊断的信心：两种检测的ROC分析
3. BAP1 immunohistochemistry and p16 FISH in the diagnosis of malignant peritoneal mesothelioma [J] . Kawai T., Kameda K., Nakanishi K., Virchows Archiv: an international journal of pathology . 2016,第Suppla1期

机译：BAP1免疫组化和p16 FISH诊断恶性腹膜间皮瘤
4. Novel computer-aided diagnosis of Mesothelioma using nuclear structure of mesothelial cells in effusion cytology specimens [C] . Akif Burak Tosun, Oleksandr Yergiyev, Soheil Kolouri, Conference on digital pathology . 2014

机译：利用渗出细胞学标本中的间皮细胞核结构对间皮瘤进行新型计算机辅助诊断
5. Functional, Volumetric, and Textural Analysis of Malignant Pleural Mesothelioma Using Computed Tomography and Deep Convolutional Neural Networks [D] . Guemundsson, Eyjólfur. 2019

机译：利用计算机断层扫描和深卷积神经网络的恶性胸腔间皮瘤的功能性，体积和纹理分析
6. FISH assay development for the detection of p16/CDKN2A deletion in malignant pleural mesothelioma [O] . Catherine T-S Chung, Gilda Da Cunha Santos, David M Hwang, -1

机译：用于检测恶性胸膜间皮瘤中p16 / CDKN2A缺失的FISH检测方法的开发
7. Role of p16 deletion and BAP1 loss in the diagnosis of malignant mesothelioma [O] . Jing Liu, Xuanzhi Liao, Yingying Gu, 2018

机译：P16缺失和BAP1损失在恶性间皮瘤的诊断中的作用

BAP1 Immunostain and CDKN2A (p16) FISH Analysis Clinical Applicability for the Diagnosis of Malignant Mesothelioma in Effusions

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