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首页> 外文期刊>Diseases of the Colon and Rectum >Comparison of a newly designed double-layered combination covered stent and D-weave uncovered stent for decompression of obstructive colorectal cancer: a prospective multicenter study.
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Comparison of a newly designed double-layered combination covered stent and D-weave uncovered stent for decompression of obstructive colorectal cancer: a prospective multicenter study.

机译：新型设计的双层组合覆膜支架和D编织未覆盖支架对梗阻性结直肠癌减压的比较：一项前瞻性多中心研究。

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PURPOSE: Stent reocclusion and migration are the most important complications after stent insertion. To overcome both problems, a double-layered combination covered stent was developed. Our purpose was to compare the efficacy and safety of the newly designed double-layered combination covered stent (Niti-S enteral colonic stent, Comvi type) and the double-wire woven uncovered stent (Niti-S enteral colonic stent, D-type) in the treatment of malignant colorectal obstructions. METHODS: Sixty-eight patients with obstructive colorectal cancer underwent stent placement for preoperative decompression (n = 30) or palliative purpose (n = 38) at 6 medical centers. Combination covered stents were used in 31 patients and uncovered stents were used in 37 patients. RESULTS: There were no significant differences between both stents in terms of technical and clinical success rates. Regarding complications after stent insertion, there was no significant difference in early stent occlusion and migration rate between the combination covered stents and the uncovered stents. Despite a trend toward lower rates of late stent occlusion in the combination covered stent group, there was no significant difference in the rate of late stent occlusion by tumor ingrowth between the 2 groups (0% vs 20%, respectively; P = .107), and late stent migration occurred significantly more often with the combination covered stent (22.2% vs 0%, respectively; P = .041). However, we observed no significant difference in the overall late-complication rates and stent patency duration between the 2 groups. CONCLUSIONS: In our study, we could not prove that the newly designed double-layered combination covered stents have preventive advantages in stent migration compared with the uncovered stent.
机译：目的：支架置入后，支架的重新闭合是最重要的并发症。为了克服这两个问题，开发了双层组合覆盖支架。我们的目的是比较新设计的双层组合覆膜支架（Niti-S肠结肠支架，Comvi型）和双丝编织未覆盖支架（Niti-S肠结肠支架，D型）的有效性和安全性。在恶性大肠梗阻的治疗中。方法：在6个医疗中心对68例阻塞性大肠癌患者进行了术前减压（n = 30）或姑息性（n = 38）支架置入术。 31例患者使用了复合覆盖支架，37例患者使用了未覆盖支架。结果：两种支架在技术和临床成功率方面均无显着差异。关于支架置入后的并发症，组合式覆膜支架与未覆盖支架在早期支架阻塞和迁移率方面无显着差异。尽管联合覆盖支架组的晚期支架闭塞率有降低的趋势，但两组之间因肿瘤向内生长的晚期支架闭塞率没有显着差异（分别为0％和20％; P = .107） ，并用覆膜支架联合覆膜支架的发生率更高（分别为22.2％和0％; P = .041）。但是，我们发现两组之间的总晚期并发症发生率和支架通畅时间没有显着差异。结论：在我们的研究中，我们无法证明新设计的双层组合覆膜支架与未覆盖的支架相比具有预防支架迁移的优势。

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