Unravelling the X in sex

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Unravelling the X in sex

机译：揭开性爱中的X

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New cytological techniques combined with genome-wide expression studies and ChIP-on-chip have revealed that random X-inactivation is not a simple one-step process that occurs uniformly across the entire chromosome, but a complex series of events with clear links to both the epigenetic silencing of autosomal genes and the imprinted X-inactivation that occurs in male meiosis. It appears to be less bizarre, as the French love to say, and as such an even better model of epigenetic gene silencing, than previously thought.

机译：新的细胞学技术与全基因组表达研究和芯片上芯片结合显示，随机X灭活不是在整个染色体上均匀发生的简单一步过程，而是一系列复杂的事件，两者之间有着明确的联系常染色体基因的表观遗传沉默和在男性减数分裂中发生的印迹X灭活。正如法国人喜欢说的那样，它似乎不像以前那样怪异，而且这样表观遗传基因沉默的模型甚至更好。

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《Developmental cell》 |2006年第6期|共4页
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正文语种 eng
中图分类普通生物学;
关键词
LINKED GENE-EXPRESSION; EARLY MOUSE EMBRYOS; CHROMOSOME INACTIVATION; DOSAGE COMPENSATION; DNA METHYLATION; XIST RNA; WIDE; DROSOPHILA; MICE; VARIEGATION;

机译：关联的基因表达;早期小鼠胚胎;染色体灭活;剂量补偿;DNA甲基化;XIST RNA;宽;果蝇;小鼠;变异;

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Unravelling the X in sex

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