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首页> 外文期刊>Digestive Diseases and Sciences >Introduction to the Hepatic Encephalopathy Scoring Algorithm (HESA).
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Introduction to the Hepatic Encephalopathy Scoring Algorithm (HESA).

机译：肝性脑病评分算法（HESA）简介。

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摘要

A primary obstacle to early diagnosis and treatment of hepatic encephalopathy (HE) is the lack of a well-validated, standardized assessment method. The purpose of this study was to present preliminary validity data on a new method of grading HE, the Hepatic Encephalopathy Scoring Algorithm (HESA), which combines clinical impressions with neuropsychological performances to characterize HE. Participants were 49 inpatients admitted for complications of end stage liver disease. Each participant's level of HE was graded using HESA and the West Haven Criteria (WHC) by independent raters blinded to each other's rating. A moderately strong association was found between the two grading methods (r = 0.60), and individual HESA clinical and neuropsychological indicators were good discriminators among grades. The results also suggest HESA may be more sensitive to mental status impairment in the middle grades of HE than WHC. These findings suggest HESA holds promise as a multi-method approach to grading all levels of HE.
机译：肝性脑病（HE）的早期诊断和治疗的主要障碍是缺乏有效的标准化评估方法。这项研究的目的是提供一种新的HE分级方法的初步有效性数据，即肝性脑病评分算法（HESA），该方法结合了临床印象和神经心理学表现来表征HE。参与者为49位因晚期肝病并发症而住院的患者。每个参与者的HE等级均由HESA和West Haven Criteria（WHC）评分，由独立评估者对彼此的等级视而不见。两种评分方法之间存在中等程度的强相关性（r = 0.60），并且各个HESA临床和神经心理学指标是各个年级之间的良好区分者。结果还表明，HESA对中年级的心理状态损害可能比WHC更敏感。这些发现表明，HESA有望成为对HE的各个级别进行分级的多方法方法。

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